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Showing 1-30 of 118 results for "

phr1254

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Keat Choong et al.
Clinical & experimental ophthalmology, 38(3), 309-313 (2010-05-08)
Herpes simplex virus (HSV) keratitis is a common cause of ocular morbidity. Resistance to aciclovir is probably under recognized. We describe three cases of aciclovir-resistant herpes simplex virus keratitis treated with systemic foscarnet and present a review of the pharmacological
Monica M Sauter et al.
Antiviral research, 109, 83-96 (2014-07-06)
Herpes simplex virus type 1 (HSV-1) is an important human pathogen which requires activation of nuclear factor-kappa B (NFκB) during its replication cycle. The persistent nature of HSV-1 infection, and the emergence of drug-resistant strains, highlights the importance of research
Christopher M Hull et al.
Postgraduate medicine, 122(5), 1-6 (2010-09-30)
Recurrent herpes simplex labialis (HSL), also known as orofacial herpes or cold sores, is a common clinical presentation of herpes simplex virus (HSV) infection. It may manifest as painful, distressing, and cosmetically displeasing vesicles on the lips, nose, and nasal
Christophe Vanpouille et al.
Current opinion in infectious diseases, 22(6), 583-587 (2009-09-04)
Epidemiological studies have demonstrated that HIV-1 and herpes simplex virus-2 (HSV-2) are responsible for two epidemics and that, by overlapping in risk populations, they reinforce the spreading of both HIV-1 disease and genital herpes. Randomized controlled trials have investigated whether
Don't let herpes melt your brain!
Paul Jhun et al.
Annals of emergency medicine, 64(6), 589-590 (2014-12-03)
Combination therapy for Bell's palsy.
J A de Ru et al.
The American journal of medicine, 126(12), e27-e27 (2013-11-23)
Alaa A Salem et al.
Journal of AOAC International, 95(6), 1644-1651 (2013-03-05)
Rapid, simple, and selective methods for determining amantadine HCI and acyclovir antiviral drugs in pharmaceutical and plasma samples were developed using 1H-NMR spectroscopy with dimethyl sulfoxide (DMSO-d6) as the solvent. Integrations of the 1H-NMR signals at 2.07 and 7.82 ppm
Howell-Jolly body-like inclusions in immunocompromised patients with antiviral treatment.
Cristian Morales-Indiano et al.
Annals of hematology, 93(12), 2091-2092 (2014-05-23)
Aciclovir and its l-valyl ester, valaciclovir.
M L Smiley et al.
Current problems in dermatology, 24, 209-218 (1996-01-01)
A 4-day-old neonate with a widespread vesicular rash.
Barry Ladizinski et al.
JAMA, 310(9), 971-972 (2013-09-05)
Axel Schubert et al.
Antiviral research, 107, 16-22 (2014-04-22)
The role of mutations in the thymidine kinase (TK, UL23) and DNA polymerase (pol, UL30) genes of herpes simplex virus (HSV) for development of different resistance phenotypes has to be exactly determined before genotypic resistance testing can be implemented in
J Gueudry et al.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 58(1), 318-320 (2013-06-13)
Varicella-zoster virus (VZV) resistance to acyclovir (ACV) has only been reported in rare cases of immunocompromised patients. We report the first case of an immunocompetent patient with ACV-resistant VZV keratitis associated with a nucleotide deletion in the VZV thymidine kinase
S Leflore et al.
Drug safety, 23(2), 131-142 (2000-08-17)
The objective of this article is to review and evaluate risks and benefits associated with the use of acyclovir in the treatment and prophylaxis of common manifestations of herpes simplex virus (HSV) infections in immunocompetent and immunocompromised patients. Information was
Towards evidence based medicine for paediatricians. Does oral aciclovir improve clinical outcome in immunocompetent children with primary herpes simplex gingivostomatitis?
B Hudson et al.
Archives of disease in childhood, 94(2), 165-167 (2009-01-23)
A patient with progressive dyspnea and multiple foci of airspace consolidation.
Keith E Boundy et al.
Chest, 145(1), 167-172 (2014-01-08)
Secondary viral encephalitis in a patient with pyogenic liver abscess.
N Sahni et al.
Anaesthesia and intensive care, 42(4), 528-530 (2014-06-27)
Determination of acyclovir in human plasma by high-performance liquid chromatography
Boulieu R, et al
Journal of Chromatography. B, Biomedical Sciences and Applications, 693(1), 233-236 (1997)
Sonia Burrel et al.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 58(1), 321-324 (2013-06-05)
Herpes simplex virus type 1 (HSV-1) is a leading cause of corneal blindness. Acyclovir (ACV) constitutes the standard treatment of HSV infections including herpetic keratitis (HK). HSV resistance to ACV is mainly described in immunocompromised patients. We describe two cases
Response.
Sam Eljamel
Journal of neurosurgery, 118(6), 1386-1386 (2013-07-23)
Darren Svirskis et al.
Pharmaceutical development and technology, 19(5), 571-576 (2013-07-19)
This study aimed at improving the oral bioavailability of acyclovir (ACV) through incorporating it into gastroretentive dosage form based on floating hollow chitosan beads. Hollow chitosan beads were prepared using a solvent free, ionotropic gelation method. The effect of formulation
Should all adults with varicella be prescribed antiviral treatment?
D Ashley R Watson
The Medical journal of Australia, 198(5), 259-259 (2013-03-19)
J Sipe et al.
The Cochrane database of systematic reviews, (2)(2), CD001869-CD001869 (2001-06-19)
The most common disorder of the facial nerve is acute idiopathic facial paralysis or Bell's palsy and there may be significant morbidity or incomplete recovery associated with severe cases. Although the cause remains unknown, recent evidence suggests a possible association
J Sipe et al.
The Cochrane database of systematic reviews, (4)(4), CD001869-CD001869 (2001-11-01)
The most common disorder of the facial nerve is acute idiopathic facial paralysis or Bell's palsy and there may be significant morbidity or incomplete recovery associated with severe cases. Although the cause remains unknown, recent evidence suggests a possible association
Shar-yin N Huang et al.
Nucleic acids research, 41(16), 7793-7803 (2013-06-19)
Chain-terminating nucleoside analogs (CTNAs) that cause stalling or premature termination of DNA replication forks are widely used as anticancer and antiviral drugs. However, it is not well understood how cells repair the DNA damage induced by these drugs. Here, we
Simple spectrophotometric determination of acyclovir in bulk drug and formulations
Basavaiah K and Prameela HC
Il Farmaco (Societa Chimica Italiana : 1989), 57(6), 443-449 (2002)
Roberto H Caraballo et al.
Seizure, 22(7), 553-559 (2013-05-07)
To analyze the electroclinical features, neuroimaging findings, treatment, and outcome of 12 patients with febrile infection-related epilepsy syndrome (FIRES). This is a retrospective study of 12 children with FIRES with a mean time of follow-up of 6.5 years carried out
André Engesland et al.
Journal of pharmaceutical sciences, 104(3), 1119-1127 (2015-01-06)
Cost-effective and efficient methods for permeability screening are crucial during early development of drugs, drug formulations, and cosmeceuticals. Alternatives to animal experiments are impelled for both economical and ethical reasons. The aim of this study was to determine the ability
B P Shelley et al.
Journal of the neurological sciences, 252(2), 177-180 (2006-12-22)
This is a case report of PCR proven herpes simplex (HSV-1) encephalitis in a 26 years old immunocompetent adult taking an unusual course of acute intracerebral haematoma after successful and complete recovery with acyclovir therapy. This transient late complication was
Aaron A R Tobian et al.
The Journal of infectious diseases, 208(5), 839-846 (2013-07-03)
The association between initiation of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection and possible herpes simplex virus type 2 (HSV-2) shedding and genital ulcer disease (GUD) has not been evaluated. GUD and vaginal HSV-2 shedding were evaluated among
Monique van Velzen et al.
The Journal of infectious diseases, 208(9), 1359-1365 (2013-08-01)
Long-term acyclovir (ACV) prophylaxis, recommended to prevent recurrent herpes simplex virus type 1 (HSV-1) ocular disorders, may pose a risk for ACV-refractory disease due to ACV resistance. We determined the effect of ACV prophylaxis on the prevalence of corneal ACV-resistant
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