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Showing 1-18 of 18 results for "RAB0252" within Papers
Agatha S Critchfield et al.
Reproductive sciences (Thousand Oaks, Calif.), 21(10), 1266-1273 (2014-02-13)
To evaluate the biocompatibility of silk gel for cervical injection. Silk gel was injected into the cervix of pregnant rats on day 13 (n = 11) and harvested at day 17. Histology of silk gel was compared with suture controls.
Andrea L Armstead et al.
International journal of nanomedicine, 11, 6195-6206 (2016-12-07)
Identifying the toxicity of nanoparticles (NPs) is an important area of research as the number of nanomaterial-based consumer and industrial products continually rises. In addition, the potential inflammatory effects resulting from pulmonary NP exposure are emerging as an important aspect
Jin-Sung Chung et al.
The Journal of investigative dermatology, 134(11), 2784-2794 (2014-06-18)
A major barrier to successful cancer immunotherapy is the tumor's ability to induce T-cell tolerance by exploiting host regulatory mechanisms. Having discovered the DC-HIL receptor, which inhibits T-cell responses by binding to syndecan-4 on effector T cells, we posited the
Tara M Weitz et al.
The American journal of pathology, 184(11), 2855-2861 (2014-09-02)
Activated microglia are associated with amyloid plaques in transgenic mouse models of cerebral amyloidosis and in human Alzheimer disease; yet, their implication in Alzheimer disease pathogenesis remains unclear. It has been suggested that microglia play dual roles depending on the
D M Bailey et al.
Acta physiologica (Oxford, England), 212(2), 175-187 (2014-05-09)
The aim of this study was to examine if erythropoietin (EPO) has the potential to act as a biological antioxidant and determine the underlying mechanisms. The rate at which its recombinant form (rHuEPO) reacts with hydroxyl (HO˙), 2,2-diphenyl-1-picrylhydrazyl (DPPH˙) and
Jere Lindén et al.
International journal of molecular sciences, 15(8), 13938-13966 (2014-08-15)
One of the hallmarks of the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a drastically reduced feed intake by an unknown mechanism. To further elucidate this wasting syndrome, we followed the effects of a single large dose (100 μg/kg) of TCDD
Xiaolu Sun et al.
BMC molecular and cell biology, 23(1), 14-14 (2022-03-21)
Pulmonary tuberculosis (TB) is a chronic infectious disease. microRNA (miR)-378 is involved in TB diagnosis. This study explored the effects of miR-378 on TB patients. A total of 126 TB patients were selected, including 63 active TB and 63 latent TB
Ryan W Walker et al.
Obesity (Silver Spring, Md.), 22(6), 1512-1519 (2014-03-13)
Obesity in childhood is associated with an inflammatory state in adipose tissue and liver, which elevates risk for diabetes and liver disease. No prior study has examined associations between pathologies occurring in adipose tissue and liver to identify elements of
Jason M Correnti et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G959-G973 (2014-04-20)
Hepatosteatosis, the ectopic accumulation of lipid in the liver, is one of the earliest clinical signs of alcoholic liver disease (ALD). Alcohol-dependent deregulation of liver ceramide levels as well as inhibition of AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor
Yu-Sheng Fang et al.
Nature communications, 5, 4824-4824 (2014-09-13)
Proteinaceous inclusions are common hallmarks of many neurodegenerative diseases. TDP-43 proteinopathies, consisting of several neurodegenerative diseases, including frontotemporal lobar dementia (FTLD) and amyotrophic lateral sclerosis (ALS), are characterized by inclusion bodies formed by polyubiquitinated and hyperphosphorylated full-length and truncated TDP-43.
Jianfei Ji et al.
Stem cells translational medicine, 3(3), 356-364 (2014-01-01)
Targeting cancer stem cells (CSCs) with immunotherapy may be an effective means to prevent recurrences in glioblastoma multiforme (GBM). It is well established that CD133 is expressed in the population of GBM tumor cells representing CSCs. This raises a possibility
Changchun Cai et al.
Hepatology (Baltimore, Md.), 60(3), 990-1002 (2014-05-07)
Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in industrialized countries. Understanding the mechanisms of APAP-induced liver injury as well as other forms of sterile liver injury is critical to improve the care of patients. Recent
Jonathan P Little et al.
Molecular and cellular neurosciences, 60, 88-96 (2014-04-29)
Microglia represent mononuclear phagocytes in the brain and perform immune surveillance, recognizing a number of signaling molecules released from surrounding cells in both healthy and pathological situations. The microglia interact with several damage-associated molecular pattern molecules (DAMPs) and recent data
Brucella Omp25 Upregulates miR-155, miR-21-5p, and miR-23b to Inhibit Interleukin-12 Production via Modulation of Programmed Death-1 Signaling in Human Monocyte/Macrophages.
Cui B, et al.
Frontiers in Immunology, 8, 708-708 (2017)
Interleukin 35 polymorphisms are associated with decreased risk of premature coronary artery disease, metabolic parameters, and IL-35 levels: the genetics of atherosclerotic disease (GEA) study.
Posadas-Sanchez R, et al.
Mediators of Inflammation, 2017, 10-10 (2017)
Ill-Hwa Kim et al.
Theriogenology, 82(3), 427-432 (2014-06-17)
The objective of this study was to compare the concentrations of inflammatory cytokines in uterine flush and serum from healthy postpartum dairy cows and cows with clinical or subclinical endometritis. Clinical endometritis was diagnosed by observation of vaginal discharges (>50%
Somiraa S Said et al.
Pharmaceutical research, 31(12), 3335-3347 (2014-05-24)
For building functional vasculature, controlled delivery of fibroblast growth factor-9 (FGF9) from electrospun fibers is an appealing strategy to overcome challenges associated with its short half-life. FGF9 sustained delivery could potentially drive muscularization of angiogenic sprouts and help regenerate stable
Diana A Alvarez Arias et al.
Cancer immunology research, 2(3), 207-216 (2014-04-30)
Tumor growth is associated with the inhibition of host antitumor immune responses that can impose serious obstacles to cancer immunotherapy. To define the potential contribution of Qa-1-restricted CD8 regulatory T cells (Treg) to the development of tumor immunity, we studied
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