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Showing 1-30 of 145 results for "V5265" within Papers
Yunmee Lho et al.
International journal of molecular sciences, 22(9) (2021-05-06)
We investigated the effectiveness of the transforming growth factor beta-1 (TGF-β) receptor inhibitor GW788388 on the epithelial to mesenchymal transition (EMT) using human peritoneal mesothelial cells (HPMCs) and examined the effectiveness of GW788388 on the peritoneal membrane using a peritoneal
Performance of Gram and Acridine-orange staining in hand phlegmon.
Camillo Theo Müller et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67(10), 1451-1452 (2014-06-11)
Ah-Rong Nam et al.
Cancer research and treatment, 52(3), 945-956 (2020-04-21)
Currently, the DNA damage response (DDR) pathway represents a key target for new cancer drug development. Advanced biliary tract cancer (BTC) has a poor prognosis because of the lack of efficacious treatment options. Although DNA repair pathway alterations have been
Arindam Mitra et al.
PloS one, 8(2), e55492-e55492 (2013-02-06)
Urinary tract infections primarily caused by uropathogenic strains of Escherichia coli (E. coli) remain a significant public health problem in both developed and developing countries. An important virulence determinant in uropathogenesis is biofilm formation which requires expression of fimbriae, flagella
Yaqing Zhang et al.
Frontiers in pharmacology, 11, 600994-600994 (2021-02-02)
Background: Drug resistance is a major obstacle in chemotherapy for ovarian cancer, wherein the up regulation of drug-resistant genes plays an important role. The cytoplasmic polyadenylation element binding protein 4 (CPEB4) is an RNA binding protein that controls mRNA cytoplasmic
Farah Naz Qamar et al.
JPMA. The Journal of the Pakistan Medical Association, 63(11), 1364-1369 (2014-01-08)
To describe the clinical profile and outcome in newborns with omphalitis managed with home or clinic-based therapy. The descriptive study was conducted from September 2004 to August 2007 in three low-income communities in Karachi, Pakistan. Newborns with omphalitis detected by
Dominique Hurtaud-Pessel et al.
Journal of AOAC International, 96(5), 1152-1157 (2013-11-29)
During the AOAC Annual Meeting held from September 30 to October 3, 2012 in Las Vegas, NV, the Expert Review Panel (ERP) on Veterinary Drug Residues reviewed data for the method for determination of residues of three triphenylmethane dyes and
Ming Chang et al.
Frontiers in pharmacology, 12, 758219-758219 (2021-10-12)
Litchi seeds have been traditionally used in Chinese herbal formula for urologic neoplasms including prostate cancer (PCa). However, the effective components of Litchi seeds and the mechanisms of their actions on PCa cell growth and metastasis remain unclear. In this
Jay W Hooper et al.
Vaccine, 28(2), 494-511 (2009-10-17)
Naturally occurring smallpox was eradicated as a result of successful vaccination campaigns during the 1960s and 1970s. Because of its highly contagious nature and high mortality rate, smallpox has significant potential as a biological weapon. Unfortunately, the current vaccine for
Daniele Musiani et al.
Cell reports, 30(4), 1208-1222 (2020-01-30)
Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers and linked to poor response to chemotherapy. Various PRMT1 inhibitors are currently under development; yet, we do not fully understand the mechanisms underpinning PRMT1 involvement in tumorigenesis and chemoresistance.
António Lourenço et al.
Applied and environmental microbiology, 79(19), 6075-6082 (2013-07-31)
The food-borne pathogen Listeria monocytogenes is the causative agent of the severe human and animal disease listeriosis. The persistence of this bacterium in food processing environments is mainly attributed to its ability to form biofilms. The search for proteins associated
Uri Ben-David et al.
Nature communications, 7, 12160-12160 (2016-07-05)
Aneuploidy and copy-number alterations (CNAs) are a hallmark of human cancer. Although genetically engineered mouse models (GEMMs) are commonly used to model human cancer, their chromosomal landscapes remain underexplored. Here we use gene expression profiles to infer CNAs in 3,108
Xingxing Gu et al.
Journal of nanoscience and nanotechnology, 14(6), 4655-4663 (2014-04-18)
In this study, hexadecyltrimethyl ammonium bromide and triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) were used as co-templates and tetraethoxysilane was used as silica source to synthesize mesoporous MCM-48, which was employed to adsorb methyl violet dye from water. The prepared MCM-48
Jinsoo Yoon et al.
Methods and protocols, 3(1) (2020-01-26)
Bioluminescent tumor cell lines are used extensively in vivo to monitor tumor growth and metastasis but rarely used in vitro to follow tumor cell behavior. Tumor cell migration is frequently studied in vitro using transwell assays, however, current methods do
Histological and histochemical methods: Theory and practice (5th ed.)
JA Kiernan
Histological and Histochemical Methods: Theory and Practice (2015)
Danielle M Grant et al.
Biology of reproduction, 102(1), 170-184 (2019-08-14)
Preimplantation equine embryos synthesize and secrete fibrinogen, which is a peculiar finding as fibrinogen synthesis almost exclusively occurs in the liver. This study investigated the hypothesis that conceptus-derived fibrinogen mediates cell adhesion during fixation. On day 21 of pregnancy, five
Francisco S Mesquita et al.
Developmental cell, 56(20), 2790-2807 (2021-10-03)
SARS-CoV-2 virions are surrounded by a lipid bilayer that contains membrane proteins such as spike, responsible for target-cell binding and virus fusion. We found that during SARS-CoV-2 infection, spike becomes lipid modified, through the sequential action of the S-acyltransferases ZDHHC20
Leo Jld van Griensven et al.
Chinese medicine, 8(1), 25-25 (2013-12-19)
The differentiation resp. death of human monocytic THP-1 cells induced by polysaccharide extracts of the medicinal mushrooms Phellinus linteus, Agaricus bisporus and Agaricus brasiliensis have been studied. This study aims to identify leads for the causal effects of these mushroom
Alexis Laurent et al.
Frontiers in bioengineering and biotechnology, 8, 581-581 (2020-07-09)
Cultured primary progenitor cell types are worthy therapeutic candidates for regenerative medicine. Clinical translation, industrial transposition, and commercial implementation of products based on such cell sources are mainly hindered by economic or technical barriers and stringent regulatory requirements. Applied research
Flávio Rodrigues Ferreira Alves et al.
Brazilian oral research, 27(1), 20-25 (2013-01-12)
This study evaluated the in vitro effects of four natural substances on the biomass of bacterial biofilms to assess their potential use as root canal irrigants. The following substances and their combinations were tested: 0.2% farnesol; 5% xylitol; 20% xylitol;
Dong-Keon Kim et al.
Cancers, 12(9) (2020-09-17)
Octamer-binding transcription factor 4 (Oct4) plays an important role in maintaining pluripotency in embryonic stem cells and is closely related to the malignancies of various cancers. Although posttranslational modifications of Oct4 have been widely studied, most of these have not
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases
Lu J, et al.
Biochemical Pharmacology, 43, 25-38 (2017)
David Brunn et al.
Cancers, 13(2) (2021-01-13)
Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that exert in tumor-suppressing or oncogenic functions via the JAK-STAT pathway.
Haineng Xu et al.
Cell reports. Medicine, 2(9), 100394-100394 (2021-10-09)
CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCNE1 overexpression would lead to increased sensitivity to low-dose WEE1 inhibition
Jorge Meneses Nunes et al.
Antimicrobial agents and chemotherapy, 57(1), 382-389 (2012-11-02)
Rhodotorula species are emergent fungal pathogens capable of causing invasive infections, primarily fungemia. They are particularly problematic in immunosuppressed patients when using a central venous catheter. In this study, we evaluated the species distribution of 51 clinical and 8 environmental
Ricardo L Berrios et al.
Dermatologic clinics, 29(1), 69-73 (2010-11-26)
The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet, represent
Marie-Anaïs Locquet et al.
Cells, 10(2) (2021-03-07)
Chordomas are rare, slow-growing tumors of the axial skeleton. These tumors are locally aggressive and refractory to conventional therapies. Radical surgery and radiation remain the first-line treatments. Despite these aggressive treatments, chordomas often recur and second-line treatment options are limited.
Manisha Taya et al.
Endocrine-related cancer, 27(4), 261-274 (2020-02-12)
Chronic inflammation promotes progression of many cancers, with circulating myeloid-derived suppressor cell (MDSC) levels correlating with poor prognosis. Here we examine effects of MDSCs on lymphangioleiomyomatosis (LAM), a rare disease occurring almost exclusively in women whereby estrogen-sensitive metastatic TSC2-null tumors
L V Lagun et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (3)(3), 18-23 (2013-09-05)
Study the intensity of formation of microbial biofilms by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus strains isolated during various forms of pyelonephritis. 150 clinical isolates of microorganisms isolated from urine ofpatientswith acute and chronic pyelonephritiswere included into the
Alan M O'Neill et al.
eLife, 10 (2021-10-20)
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important emerging zoonotic pathogen that causes severe skin infections. To combat infections from drug-resistant bacteria, the transplantation of commensal antimicrobial bacteria as a therapeutic has shown clinical promise. We screened a collection of diverse
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