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  • MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains.

MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains.

European journal of medicinal chemistry (2017-03-17)
Özgür Devrim Can, Derya Osmaniye, Ümide Demir Özkay, Begüm Nurpelin Sağlık, Serkan Levent, Sinem Ilgın, Merve Baysal, Yusuf Özkay, Zafer Asım Kaplancıklı
ABSTRACT

In the present work, 15 new N'-(arylidene)-4-(1-(prop-2-yn-1-yl)-1H-benzo[d]imidazol-2-yl)benzohydrazide (4a-4o) were designed and synthesized. The structures of the synthesized compounds were elucidated using FT-IR,

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ampliflu Red, suitable for fluorescence, ≥98.0% (HPLC)
Sigma-Aldrich
Benzimidazole, 98%