Adventitious Agent Testing by NGS: A Comprehensive Solution with Targeted and Non-targeted Methods

WEBINAR

An important aspect of viral safety assurance for biologics is a panel of orthogonal virus detection assays performed during cell line characterization. Increasingly, regulations are being updated to recommend the use of molecular methods for biosafety testing, especially to replace outdated animal-based testing.

In this context, the correct selection of assays is critical to retain sufficient breadth of virus detection and sensitivity to mitigate the risk of contamination events. In this webinar, we explore the use of non-targeted next generation sequencing (NGS), combined with targeted molecular methods, to encompass a suitable range of viruses to meet specific regulatory expectations.

In this webinar, you will learn:

• What regulators expect from your cell line characterization package for adventitious virus testing
• Different methods employed in targeted and non-targeted approaches
• How our orthogonal NGS approaches comply with ICH Q5A(R2) and other recent regulatory updates
• How molecular methods can support sustainability and 3R initiatives by replacing animal testing