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Merck
CN

CLDN14

claudin 14

别名:
DFNB29
物种:
UniProtKB ID:
基因ID:
  • Human(23562) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
  • Mouse(56173) claudin 14
  • Rat(304073) claudin 14
  • domestic cat(101082083) claudin 14
  • chicken(427982) claudin 14
  • domestic guinea pig(100726532) claudin 14
  • naked mole-rat(101724744) claudin 14
  • cow(783180) claudin 14
  • sheep(101109068) claudin 14
  • dog(487751) claudin 14

Custom & Knockdown Gene Products

Antibodies

产品编号
说明
物种反应性
应用
Monoclonal Anti-CLDN14 antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)

esiRNA

产品编号
说明
物种
MISSION® esiRNA, targeting human CLDN14,
物种
human