DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
别名:
NC2-alpha
物种:
Human DRAP1 (10589), Mouse Drap1 (66556), Rat Drap1 (293674), cow DRAP1 (540345), Goat DRAP1 (100861124), sheep DRAP1 (101111673), dog DRAP1 (476018), domestic cat DRAP1 (101101589), Zebrafish drap1 (321681), domestic guinea pig Drap1 (100734988)
UniProtKB ID:
基因ID:
- Human(10589) Summary: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
- Mouse(66556) Dr1 associated protein 1 (negative cofactor 2 alpha)
- Rat(293674) Dr1 associated protein 1 (negative cofactor 2 alpha)
- cow(540345) DR1-associated protein 1 (negative cofactor 2 alpha)
- Goat(100861124) DR1-associated protein 1 (negative cofactor 2 alpha)
- sheep(101111673) DR1-associated protein 1 (negative cofactor 2 alpha)
- dog(476018) DR1-associated protein 1 (negative cofactor 2 alpha)
- domestic cat(101101589) DR1-associated protein 1 (negative cofactor 2 alpha)
- Zebrafish(321681) DR1-associated protein 1 (negative cofactor 2 alpha)
- domestic guinea pig(100734988) DR1-associated protein 1 (negative cofactor 2 alpha)
- naked mole-rat(101706865) DR1-associated protein 1 (negative cofactor 2 alpha)
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Antibodies
产品编号
说明
物种反应性
应用
Anti-DRAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot