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Merck
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GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

Custom & Knockdown Gene Products

Small Molecule - Agonist

产品编号
说明
物种
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
Piperidine-4-sulfonic acid, ,
物种
human
γ-氨基丁酸, ≥99%,
物种
human, rat
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

产品编号
说明
物种
反式-脱氢雄甾酮, ≥99%,
物种
human, rat
普鲁泊福, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
依托咪酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Antagonist

产品编号
说明
物种
Ro 15-4513, solid,
物种
rat, human
SR-95531, ≥98% (HPLC), powder,
物种
human
反式-脱氢雄甾酮, ≥99%,
物种
human, rat
氟马西尼, United States Pharmacopeia (USP) Reference Standard,
物种
human
Ganaxolone, solid, ≥98% (HPLC),
物种
human, mouse

Antibodies

产品编号
说明
物种反应性
应用
Anti GABRA5 Antibody, clone 23GB5505, Rabbit Monoclonal, clone 23GB5505, recombinant rabbit monoclonal, expressed in HEK293 cells,
物种反应性
human, rat
应用
flow cytometry
western blot
Anti-GABA A Receptor α 5 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
物种反应性
human, mouse
应用
immunofluorescence
western blot
Anti-GABRA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-GABRA5, affinity isolated antibody,
物种反应性
horse, human, rabbit
应用
western blot

Small Molecule - Inhibitor

产品编号
说明
物种
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
(±)-Vigabatrin, ,
物种
human
普鲁泊福, 97%,
物种
human
托吡酯, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

产品编号
说明
物种
L-655,708, ≥98% (HPLC), powder,
物种
human
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

esiRNA

产品编号
说明
物种
MISSION® esiRNA, targeting human GABRA5,
物种
human