LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
别名:
MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
物种:
Human LAMTOR3 (8649), Mouse Lamtor3 (56692), Rat Lamtor3 (362045), dog LAMTOR3 (478492), naked mole-rat Lamtor3 (101702297), cow LAMTOR3 (533155), domestic cat LAMTOR3 (101099376), chicken LAMTOR3 (425210), Zebrafish lamtor3 (553597), domestic guinea pig Lamtor3 (100727855)
UniProtKB ID:
基因ID:
- Human(8649) Summary: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
- Mouse(56692) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- Rat(362045) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- dog(478492) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- naked mole-rat(101702297) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- cow(533155) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- domestic cat(101099376) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- chicken(425210) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- Zebrafish(553597) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- domestic guinea pig(100727855) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
- sheep(101110413) late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
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