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Merck
CN

PTPRJ

protein tyrosine phosphatase, receptor type, J

别名:
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
物种:
UniProtKB ID:
基因ID:
  • Human(5795) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19271) protein tyrosine phosphatase, receptor type, J
  • Rat(29645) protein tyrosine phosphatase, receptor type, J
  • chicken(395330) protein tyrosine phosphatase, receptor type, J
  • Domestic Rabbit(100347798) protein tyrosine phosphatase, receptor type, J
  • domestic cat(101086598) protein tyrosine phosphatase, receptor type, J
  • dog(483617) protein tyrosine phosphatase, receptor type, J
  • Horse(100058689) protein tyrosine phosphatase, receptor type, J
  • cow(508150) protein tyrosine phosphatase, receptor type, J
  • sheep(101121292) protein tyrosine phosphatase, receptor type, J
  • domestic guinea pig(100729887) protein tyrosine phosphatase, receptor type, J
  • naked mole-rat(101726039) protein tyrosine phosphatase, receptor type, J

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ELISA

Product Number
说明
物种
人DEP-1 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

Product Number
说明
物种反应性
应用
Monoclonal Anti-CD148-APC antibody produced in mouse, clone MEM-CD148/05,
物种反应性
应用
flow cytometry
Anti-Protein-tyrosine phosphatase eta (CD148) Antibody, clone 8A-1, clone 8A-1, from hamster(Syrian),
物种反应性
mouse
应用
flow cytometry
immunohistochemistry

western blot
Anti-PTPRJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-CD148 antibody produced in mouse, clone MEM-CD148/05, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
Anti-CD148/DEP-1 Antibody, clone Ab1 (Azide Free), clone Ab 1, from mouse,
物种反应性
human, mouse
应用
immunohistochemistry
immunoprecipitation (IP)

inhibition assay

western blot

Proteins

Product Number
说明
物种
DEP1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物种
human

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Ptprj,
物种
mouse
MISSION® esiRNA, targeting human PTPRJ,
物种
human