SSRP1
structure specific recognition protein 1
别名:
FACT, FACT80, T160
物种:
Human SSRP1 (6749), Mouse Ssrp1 (20833), Rat Ssrp1 (81785), cow SSRP1 (282082), dog SSRP1 (475970), domestic cat SSRP1 (101089296), Horse SSRP1 (100066933), naked mole-rat Ssrp1 (101696992), sheep SSRP1 (101104524), domestic guinea pig Ssrp1 (100723239)
UniProtKB ID:
基因ID:
- Human(6749) Summary: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008]
- Mouse(20833) structure specific recognition protein 1
- Rat(81785) structure specific recognition protein 1
- cow(282082) structure specific recognition protein 1
- dog(475970) structure specific recognition protein 1
- domestic cat(101089296) structure specific recognition protein 1
- Horse(100066933) structure specific recognition protein 1
- naked mole-rat(101696992) structure specific recognition protein 1
- sheep(101104524) structure specific recognition protein 1
- domestic guinea pig(100723239) structure specific recognition protein 1
- chicken(396509) structure specific recognition protein 1
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Antibodies
产品编号
说明
物种反应性
应用
Anti-SSRP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot