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Merck
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TAB3

TGF-beta activated kinase 1/MAP3K7 binding protein 3

别名:
MAP3K7IP3, NAP1
物种:
UniProtKB ID:
基因ID:
  • Human(257397) Summary: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(66724) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • Rat(317546) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • dog(491807) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • domestic guinea pig(100726447) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • Horse(100051087) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • domestic cat(101101545) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • sheep(101119184) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • chicken(418588) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • naked mole-rat(101718111) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • Zebrafish(566547) TGF-beta activated kinase 1/MAP3K7 binding protein 3
  • cow(788288) TGF-beta activated kinase 1/MAP3K7 binding protein 3

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Antibodies

Product Number
说明
物种反应性
应用
Anti-TAB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-TAB3 Antibody, clone 3Y6T7, Rabbit Monoclonal, ,
物种反应性
mouse
应用
western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting human TAB3,
物种
human