TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
别名:
4-1BB-L, CD137L
物种:
Human TNFSF9 (8744), Mouse Tnfsf9 (21950), Rat Tnfsf9 (353218), dog TNFSF9 (476729), domestic cat TNFSF9 (101087207), cow TNFSF9 (521748), sheep TNFSF9 (101108388), domestic guinea pig Tnfsf9 (101788800), naked mole-rat Tnfsf9 (101711392)
UniProtKB ID:
基因ID:
- Human(8744) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
- Mouse(21950) tumor necrosis factor (ligand) superfamily, member 9
- Rat(353218) tumor necrosis factor (ligand) superfamily, member 9
- dog(476729) tumor necrosis factor (ligand) superfamily, member 9
- domestic cat(101087207) tumor necrosis factor (ligand) superfamily, member 9
- cow(521748) tumor necrosis factor (ligand) superfamily, member 9
- sheep(101108388) tumor necrosis factor (ligand) superfamily, member 9
- domestic guinea pig(101788800) tumor necrosis factor (ligand) superfamily, member 9
- naked mole-rat(101711392) tumor necrosis factor (ligand) superfamily, member 9
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ELISA
Product Number
说明
物种
Antibodies
Product Number
说明
物种反应性
应用
Monoclonal Anti-TNFSF9 antibody produced in mouse, clone 1D7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-TNFSF9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-TNFSF9 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-4-1BBL/CD137L Antibody, clone 8E5D6, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Proteins
Product Number
说明
物种
4-1BBL human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
物种
human
esiRNA
Product Number
说明
物种