CN

277762

Sigma-Aldrich

D-(+)-乳酸甲酯

greener alternative

98%, optical purity ee: 96% (GLC)

别名:
(R)-(+)-乳酸甲酯, D-乳酸甲酯
线性分子式:
CH3CH(OH)CO2CH3
CAS号:
分子量:
104.10
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

100

测定

98%

旋光性

[α]21/D +8.4°, neat

光学纯度

ee: 96% (GLC)

环保替代产品特性

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

折射率

n20/D 1.413 (lit.)

bp

144-145 °C (lit.)

密度

1.09 g/mL at 25 °C (lit.)

环保替代产品分类

Aligned

SMILES string

COC(=O)[C@@H](C)O

InChI

1S/C4H8O3/c1-3(5)4(6)7-2/h3,5H,1-2H3/t3-/m1/s1

InChI key

LPEKGGXMPWTOCB-GSVOUGTGSA-N

一般描述

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry.This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries. Click here for more information.

应用

(+)- 甲基D-乳酸甲酯可用作不对称合成制备以下物质的原料:
  • 新酒霉素,其是一种大环内酯,包含12元大环内酯,可用作强效生物制剂。
  • PM-toxin A。

它也可以与D-(-)-酒石酸一起用作手性池,用于通过Trost-Rychnovsky炔重排、Horner-Wadsworth-Emmons烯化以及Corey-Bakshi-Shibata反应进行separacene A和B的立体选择性全合成。

包装

5 g in glass bottle

象形图

FlameExclamation mark

警示用语:

Warning

危险声明

预防措施声明

靶器官

Respiratory system

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

RIDADR

UN 3272 3 / PGIII

WGK Germany

WGK 1

闪点(F)

120.2 °F - closed cup

闪点(C)

49 °C - closed cup

分析证书

原产地证书 (CofO)

Asymmetric total synthesis of PM-toxin A, a corn host-specificpathotoxin
Hayakawa H, et al.
Chemical Communications (Cambridge, England), 66(13), 1219-1220 (1997)
Total synthesis of neomethymycin and novamethymycin
O Hong-Se and K Han-Young
Tetrahedron, 66(24), 4307-4317 (2010)
Total synthesis of marine natural products separacenes A and B
D Subhendu and G Rajib Kumar
Organic & Biomolecular Chemistry, 15(22), 4842-4850 (2017)
Nicole Borho et al.
Organic & biomolecular chemistry, 1(23), 4351-4358 (2003-12-20)
Chiral recognition and subsequent selective self-organisation into hydrogen-bonded n-mers is observed in supersonic methyl lactate expansions. The nu(OH) and nu(C=O)-vibrations are investigated by ragout-jet FTIR-spectroscopy and lead to the assignment of homo- and heterochiral clusters of at least three different...
Nicole Borho et al.
Physical chemistry chemical physics : PCCP, 8(38), 4449-4460 (2006-09-27)
Intermolecular hydrogen bonding competes with an intramolecular hydrogen bond when methanol binds to an alpha-hydroxyester. Disruption of the intramolecular OH...O=C contact in favour of a cooperative OH...OH...O=C sequence is evidenced by FTIR spectroscopy for the addition of methanol to the...

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