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Merck
CN

845875P

Avanti

18:1 Lyso PC

Avanti Research - A Croda Brand

别名:

1-(9Z-十八烯酰基)-sn-甘油-3-磷酸胆碱; PC(18:1(9Z)/ 0:0); 110688

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About This Item

经验公式(希尔记法):
C26H52NO7P
CAS号:
分子量:
521.67
UNSPSC代码:
51191904
NACRES:
NA.25

描述

1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine

检测方案

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

形式

powder

包装

pkg of 2 × 100 mg (845875P-200mg)
pkg of 5 × 100 mg (845875P-500mg)
pkg of 1 × 25 mg (845875P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

SMILES字符串

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C26H52NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h12-13,25,28H,5-11,14-24H2,1-4H3/b13-12-/t25-/m1/s1

InChI key

YAMUFBLWGFFICM-PTGWMXDISA-N

一般描述

溶血磷脂酰胆碱(LPC)是一种溶血磷脂介质。 这种具有生物活性的促炎脂质是通过病理活动产生的。它是氧化型低密度脂蛋白(Ox-LDL)的重要成分之一。

应用

18:1的溶血PC适合用作溶血磷脂介质,以比较鞘氨醇磷酸胆碱(SPC)的作用。 它已被用作酵母氮基(YNB)培养基中的补充物,以挽救胆碱营养缺陷。

生化/生理作用

溶血磷脂酰胆碱(LPC)是氧化低密度脂蛋白(Ox-LDL)表现动脉粥样硬化活性的关键因素。它可改变在内皮细胞、平滑肌细胞,单核细胞、巨噬细胞、T细胞中的作用,从而参与动脉粥样硬化和炎症性疾病的发生。LPC可激活蛋白激酶C、细胞外信号调节激酶、蛋白酪氨酸激酶、以及作为第二信使的Ca(2+)。

包装

5 mL透明玻璃密封安瓿瓶(845875P-200mg)
5 mL透明玻璃密封安瓿瓶(845875P-25mg)
5 mL透明玻璃密封安瓿瓶(845875P-500mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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