G2417
甲磺酸加贝酯
analytical standard, for drug analysis
别名:
4-(6-胍基己酰氧基)苯甲酸乙酯甲磺酸盐, 4-[[6-[(氨基亚氨基甲基)氨基]-1-氧己基]氧]苯甲酸乙酯 甲磺酸盐, 福耶
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关于此项目
经验公式（希尔记法）:
C16H23N3O4 · CH4O3S
化学文摘社编号:
分子量:
417.48
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
质量水平
表单
solid
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CS(O)(=O)=O.CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1
InChI
1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
InChI key
DNTNDFLIKUKKOC-UHFFFAOYSA-N
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一般描述
Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases, which finds therapeutic applications in the treatment of disseminated intravascular coagulation and pancreatitis. It also plays the role of an anticoagulant in hemodialysis therapy.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
S Aosasa et al.
Shock (Augusta, Ga.), 15(2), 101-105 (2001-02-28)
If the inflammatory response becomes excessive or uncontrolled by some stimuli, inappropriate inflammatory responses occur. Monocytes are extremely important cells for regulating the cytokine network and tumor necrosis factor alpha (TNFalpha) and interleukin- (IL) 10, which are mainly synthesized by
Tomoki Nishiyama et al.
The American journal of emergency medicine, 30(7), 1219-1223 (2011-12-30)
We hypothesized that antithrombin is more effective for disseminated intravascular coagulation (DIC) than is gabexate mesilate, which is a protease inhibitor, suggested from the previous studies. Initially, we compared the effects of antithrombin and gabexate mesilate for treating infection-related DIC.
Hideo Yasunaga et al.
Pancreas, 42(2), 260-264 (2012-09-25)
Despite a lack of evidence, gabexate mesylate (GM) is routinely used for the treatment of acute pancreatitis (AP) in some countries. The present study examined the effect and cost of GM for AP treatment using the Japanese Diagnosis Procedure Combination
Maria Dorly Del Curto et al.
Journal of pharmaceutical sciences, 100(8), 3251-3259 (2011-04-06)
It is well known that the intestinal stability and absorption of protein drugs are improved when enzyme inhibitors/permeation enhancers are coadministered. Recently, it was hypothesized that an increased effectiveness of these adjuvants might be achieved by timing their release prior
James A Reihill et al.
Biomolecules, 10(4) (2020-04-02)
Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease activities. Cockroach allergy is a major global health issue, with cockroaches containing considerable serine trypsin-like protease (TLP) activity. The
商品
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
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