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形式
powder or solid
分子量
5,000-25,000
颜色
white to light yellow
应用
cell analysis
储存温度
−20°C
InChI
1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI key
HNDVDQJCIGZPNO-YFKPBYRVSA-N
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相关类别
一般描述
聚-L-组氨酸是一种两性化合物。结构中的咪唑环可进行质子化−去质子化反应。
应用
聚L-组氨酸已用于：
- 作为聚阳离子分散多壁碳纳米管(MWCNT)
- 作为多离子化合物研究其破坏细胞外包膜病毒膜的能力
- 通过在细胞水平上和在体内的抗朊毒体(prion)分析，进行其抗朊毒体活性筛选
生化/生理作用
聚L-组氨酸(Phis)共聚物具有生物相容性、pH响应性和较低的毒性。它具有逃逸内溶酶体的功能。聚L组氨酸与聚乙二醇−聚(d,l-丙交酯) (PEG-PLA)的共聚物可有效递送阿霉素。pH敏感性聚l-组氨酸共聚物胶束可在酸性微环境中递送抗癌药物。
分析说明
分子量 (MALLS)。
其他说明
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.
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