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文件

108898

Sigma-Aldrich

4-硝基邻苯二胺

98%

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别名:
1,2-二氨基-4-硝基苯
线性分子式:
O2NC6H3(NH2)2
CAS号:
99-56-9
分子量:
153.14
Beilstein:
608106
EC 号:
202-766-3
MDL编号:
MFCD00007724
eCl@ss:
39030501
PubChem化学物质编号:
24846835
NACRES:
NA.22

质量水平

100

检测方案

98%

mp

199-201 °C (lit.)

溶解性

1 N HCl: ethanol, 1:1: soluble 50 mg/mL

SMILES string

Nc1ccc(cc1N)[N+]([O-])=O

InChI

1S/C6H7N3O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,7-8H2

InChI key

RAUWPNXIALNKQM-UHFFFAOYSA-N

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应用

4-硝基邻苯二胺被用于研究 体外 活化 4-硝基邻苯二胺为 鼠伤寒沙门氏菌 菌株 TA98 的有效诱变剂 。

生化/生理作用

4-硝基邻苯二胺是一种直接作用的诱变剂 。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302 - H317

危险分类

Acute Tox. 4 Oral - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Nahid Mashkouri Najafi et al.
Analytica chimica acta, 714, 82-88 (2012-01-17)
Herein, ultrasound-assisted emulsification microextraction (USAEME) and dispersive liquid-liquid microextraction (DLLME) methods based on applying low-density organic solvents have been critically compared for the speciation of inorganic selenium, Se(IV) (selenite) and Se(VI) (selenate) in environmental water samples by gas chromatography-flame ionization
J M Gentile et al.
Mutation research, 250(1-2), 79-86 (1991-09-01)
Chlorophyllin, the sodium and copper salt of chlorophyll, chlorophyll a, and chlorophyll b were tested for their ability to inhibit the mutagenic activity of the direct-acting mutagen 4-nitro-o-phenylenediamine (NOP) and its plant-activated mutagenic enhancement. All three forms of chlorophyll were
K Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1475-1482 (2002-10-22)
The antimutagenic effect of benzene, chloroform, acetone and methanol fractions from Terminalia arjuna, a well-known medicinal plant, was determined against Acid Black dye, 2-aminofluorene (2AF) and 4-nitro-o-phenylenediamine (NPD) in TA98 Frameshift mutagen tester strain of Salmonella typhimurium. Among the different
Andreas Kiontke et al.
PloS one, 11(12), e0167502-e0167502 (2016-12-03)
Over the past decades, electrospray ionization for mass spectrometry (ESI-MS) has become one of the most commonly employed techniques in analytical chemistry, mainly due to its broad applicability to polar and semipolar compounds and the superior selectivity which is achieved
S J Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38(12), 1113-1119 (2000-10-18)
A fraction isolated from Terminalia arjuna was studied for its antimutagenic effect against 4-nitro-o-phenylenediamine (NPD) in TA98, sodium azide in TA100 and 2-aminofluorene (2AF, S9-dependent), a promutagen, in both TA98 and TA 100 tester strains of Salmonella typhimurium using the
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