109266
氨基胍重碳酸盐
97%
别名:
氨基胍碳酸氢盐, 氨基胍酸式碳酸盐
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关于此项目
线性分子式:
NH2NHC(=NH)NH2 · H2CO3
化学文摘社编号:
分子量:
136.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-956-7
Beilstein/REAXYS Number:
3569869
MDL number:
产品名称
氨基胍重碳酸盐, 97%
InChI key
OTXHZHQQWQTQMW-UHFFFAOYSA-N
InChI
1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)
SMILES string
OC(O)=O.NNC(N)=N
assay
97%
mp
170-172 °C (dec.) (lit.)
solubility
H2O: soluble 2.7 g/L at 20 °C
H2O: soluble 3.3 g/L at 30 °C
functional group
amine
hydrazine
Quality Level
Application
氨基胍重碳酸盐用于研究在 5 型腺病毒感染的大鼠胚胎细胞培养物中添加多胺的效果。
Biochem/physiol Actions
氨基胍重碳酸盐保护感染了腺病毒的细胞避免发生染色体损伤。氨基胍是一种二胺氧化酶（存在于胎牛血清中）的特异性和高效性抑制剂。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
危险化学品
此项目有
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Catiúcia R M O Matos et al.
Dalton transactions (Cambridge, England : 2003), 49(45), 16359-16367 (2020-05-28)
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A J Bellett et al.
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Adenovirus uncouples DNA replication from polyamine biosynthesis and causes chromosome aberrations in rodent cells. Addition of polyamines protected infected cells from this chromosome damage. Spermine was the only individual polyamine which protected. The diamine oxidase inhibitor aminoguanidine also protected. Neither
Sebastiano Intagliata et al.
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W A Gahl et al.
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The inhibitory effect of the polyamines, spermidine and spermine, on the proliferation of human fibroblasts in culture was found to be reversed by the addition of aminoguanidine (AM), a specific and highly effective inhibitor of diamine oxidase (DAO) present in
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