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Merck
CN

112208

4-硝基苯甲酰氯

98%

别名:

p-Nitrobenzoyl chloride

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关于此项目

线性分子式:
O2NC6H4COCl
化学文摘社编号:
分子量:
185.56
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-517-4
Beilstein/REAXYS Number:
473192
MDL number:
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产品名称

4-硝基苯甲酰氯, 98%

InChI key

SKDHHIUENRGTHK-UHFFFAOYSA-N

InChI

1S/C7H4ClNO3/c8-7(10)5-1-3-6(4-2-5)9(11)12/h1-4H

SMILES string

[O-][N+](=O)c1ccc(cc1)C(Cl)=O

assay

98%

form

solid

bp

202-205 °C/105 mmHg (lit.)

mp

71-74 °C (lit.)

functional group

acyl chloride
nitro

Quality Level

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Application

<ul>
<li><strong>[11C]PiB的自动合成::</strong> 4-硝基苯甲酰氯被用于[11C]PiB的自动合成,[11C]PiB是一种用于淀粉样蛋白PET成像的放射性药物,研究突出了其在增强神经成像技术方面的作用 (Singh et al., 2024)。</li>
</ul>

General description

对硝基苯甲酰氯与三苯基膦盐反应,通过分子内维蒂希反应合成苯并呋喃(潜在正电子发射断层扫描 (PET) 示踪剂)。它已被用于二醇(雄烯二醇,前列腺癌的内源性增殖剂)的衍生化

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

215.6 °F - closed cup

flash_point_c

102 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Masahiro Ono et al.
Journal of medicinal chemistry, 49(9), 2725-2730 (2006-04-28)
A novel series of benzofuran derivatives as potential positron emission tomography (PET) tracers targeting amyloid plaques in Alzheimer's disease (AD) were synthesized and evaluated. The syntheses of benzofurans were successfully achieved by an intramolecular Wittig reaction between triphenylphosphonium salt and
Tatsuya Higashi et al.
Steroids, 71(11-12), 1007-1013 (2006-09-19)
Androstenediol (Adiol, androst-5-ene-3beta,17beta-diol) is suspected of being an endogenous proliferation agent of prostate cancer (PCa) even after androgen deprivation therapy (ADT). A liquid chromatography-electron capture atmospheric pressure chemical ionization-mass spectrometric (LC-ECAPCI-MS) method for the determination of Adiol in prostatic tissue
Meng-Ge Huangfu et al.
Nanomaterials (Basel, Switzerland), 11(2) (2021-03-07)
The rapid development of advanced high-frequency mobile communication techniques has advanced urgent requirements for polymer materials with high-temperature resistance and good dielectric properties, including low dielectric constants (low-Dk) and low dielectric dissipation factors (low-Df). The relatively poor dielectric properties of
[Experimental establishment of the maximum permissible concentration of para-nitrobenzoylchloride in the air of a work area].
M Ia Kudria et al.
Gigiena truda i professional'nye zabolevaniia, (9)(9), 47-48 (1984-09-01)
Tatsuya Higashi et al.
Steroids, 71(7), 609-617 (2006-04-20)
The liquid chromatography-mass spectrometry (LC-MS) methods were developed and validated for the determination of testosterone (T) in the brain and serum of rats and of 5alpha-androstane-3alpha,17beta-diol (ADIOL), a metabolite of T, in the brain of rats. After derivatization of T

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