质量水平
方案
98%
表单
solid
沸点
245 °C (lit.)
mp
75-77 °C (lit.)
储存温度
2-8°C
SMILES字符串
CN(C)C(=S)N(C)C
InChI
1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3
InChI key
MNOILHPDHOHILI-UHFFFAOYSA-N
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一般描述
四甲基硫脲分子表现出具有氢键堆积较弱的晶体学上双重对称性，使分子可连接形成层。
应用
四甲基硫脲可与四甲基硒脲形成BF3加合物。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Alexius Freyberger et al.
Toxicology, 217(2-3), 169-175 (2005-11-22)
N,N,N',N'-Tetramethylthiourea (TMTU) is a rat goitrogen inducing thyroid hyperplasia, hypertrophy, and tumor formation. Little is known about the exact underlying mechanism of action. As thyroid peroxidase (TPO) and type I iodothyronine deiodinase (ID-I) have been established as targets of goitrogenic
Allen Mambanda et al.
Dalton transactions (Cambridge, England : 2003), 39(15), 3595-3608 (2010-04-01)
The rate of displacement of the aqua ligands by three neutral nucleophiles (Nu) of different steric demands, namely thiourea (tu), N,N'-dimethylthiourea (dmtu) and N,N,N',N'-tetramethylthiourea (tmtu) and an anionic nucleophile (I(-)) in complexes of the form [{Pt(H(2)O)}(2)(N,N,N',N'-tetrakis(2-pyridylmethyl)-N(CH(2))(n)N](CF(3)SO(3))(4), n = 2 (En);
Y Usson et al.
Journal of neurocytology, 17(5), 639-648 (1988-10-01)
The proliferation of Schwann cells in the sciatic nerve of chick was studied from day 11 to day 27 of development in control and thyroid-deficient embryos. Hypothyroidism was induced by tetramethylthiourea injection on days 8 and 19 of incubation. The
[Effect of thyroid deficiency on cutaneous nerve development in chickens].
R Saxod et al.
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 294(1), 19-24 (1982-01-04)
A Shukla et al.
Cancer research, 61(5), 1791-1795 (2001-03-31)
Crystalline silica has been classified as a group 1 human carcinogen in the lung. However, its mechanisms of action on pulmonary epithelial cells which give rise to lung cancers are unclear. Using a nontransformed alveolar type II epithelial cell line
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