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Merck
CN

115169

四甲基硫脲

98%

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线性分子式:
(CH3)2NCSN(CH3)2
化学文摘社编号:
分子量:
132.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-488-0
Beilstein/REAXYS Number:
1744916
MDL number:
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产品名称

四甲基硫脲, 98%

InChI key

MNOILHPDHOHILI-UHFFFAOYSA-N

InChI

1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3

SMILES string

CN(C)C(=S)N(C)C

assay

98%

form

solid

bp

245 °C (lit.)

mp

75-77 °C (lit.)

storage temp.

2-8°C

Quality Level

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Application

四甲基硫脲可与四甲基硒脲形成BF3加合物

General description

四甲基硫脲分子表现出具有氢键堆积较弱的晶体学上双重对称性,使分子可连接形成层

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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T Sakamoto et al.
The American journal of physiology, 276(6 Pt 1), C1391-C1397 (1999-06-11)
Obesity is associated with hyperinsulinemia and elevated concentrations of tumor necrosis factor-alpha (TNF-alpha) in adipose tissue. TNF-alpha has been implicated as an inducer of the synthesis of plasminogen activator inhibitor-1 (PAI-1), the primary physiological inhibitor of fibrinolysis, mediated by plasminogen
Andrew Churg et al.
Toxicology and applied pharmacology, 208(1), 37-45 (2005-09-17)
Air pollution particles (PM) are known to elicit an acute inflammatory response in vivo that is mediated in part through PM-induced activation of the NF-kappaB signaling pathway. Many of the details of this process and particularly where in the cell
Y Usson et al.
Journal of neurocytology, 17(5), 639-648 (1988-10-01)
The proliferation of Schwann cells in the sciatic nerve of chick was studied from day 11 to day 27 of development in control and thyroid-deficient embryos. Hypothyroidism was induced by tetramethylthiourea injection on days 8 and 19 of incubation. The
Allen Mambanda et al.
Dalton transactions (Cambridge, England : 2003), 39(15), 3595-3608 (2010-04-01)
The rate of displacement of the aqua ligands by three neutral nucleophiles (Nu) of different steric demands, namely thiourea (tu), N,N'-dimethylthiourea (dmtu) and N,N,N',N'-tetramethylthiourea (tmtu) and an anionic nucleophile (I(-)) in complexes of the form [{Pt(H(2)O)}(2)(N,N,N',N'-tetrakis(2-pyridylmethyl)-N(CH(2))(n)N](CF(3)SO(3))(4), n = 2 (En);
Alexius Freyberger et al.
Toxicology, 217(2-3), 169-175 (2005-11-22)
N,N,N',N'-Tetramethylthiourea (TMTU) is a rat goitrogen inducing thyroid hyperplasia, hypertrophy, and tumor formation. Little is known about the exact underlying mechanism of action. As thyroid peroxidase (TPO) and type I iodothyronine deiodinase (ID-I) have been established as targets of goitrogenic

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