128791
5-喹啉醇
99%
别名:
5-羟基喹啉
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关于此项目
经验公式（希尔记法）:
C9H7NO
化学文摘社编号:
分子量:
145.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-428-4
Beilstein/REAXYS Number:
114514
MDL number:
产品名称
5-喹啉醇, 99%
InChI key
GYESAYHWISMZOK-UHFFFAOYSA-N
InChI
1S/C9H7NO/c11-9-5-1-4-8-7(9)3-2-6-10-8/h1-6,11H
SMILES string
Oc1cccc2ncccc12
assay
99%
form
solid
mp
223-226 °C (lit.)
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Application
5-Quinolinol (5-Hydroxyquinoline) was used as an internal standard in the reaction to measure morphine concentration in serum or plasma. It was also used as a lipophilic chelator and it decreased the rate of deoxygenation.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
R Deslauriers et al.
Biochimica et biophysica acta, 886(3), 319-326 (1986-05-29)
A spectrophotometric assay has been devised to measure oxygen consumption non-invasively in intact murine red cells parasitized by Plasmodium berghei. The method uses oxyhemoglobin in the erythrocytes both as a source of oxygen and as an indicator of oxygen consumption.
M Hollstein et al.
Journal of the National Cancer Institute, 60(2), 405-410 (1978-02-01)
Quinoline, a hepatocarcinogen in rats, and 23 quinoline derivatives were tested for mutagenic activity with the Ames Salmonella typhimurium assay. Quinoline, 5-hydroxyquinoline, and 8-hydroxyquinoline were mutagenic in strain TA 100 when Aroclor 1254-induced rat (male outbred Sprague-Dawley) liver homogenate was
Analysis of morphine in serum by high performance liquid chromatography with amperometric detection.
H Vandenberghe et al.
Therapeutic drug monitoring, 4(3), 307-314 (1982-01-01)
In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasma. The separation of morphine and the internal standard 5-hydroxyquinoline, from interfering compounds
Markus Brinkmann et al.
Chemical research in toxicology, 32(4), 698-707 (2019-03-22)
Hydroxylation of polyaromatic compounds through cytochromes P450 (CYPs) is known to result in potentially estrogenic transformation products. Recently, there has been an increasing awareness of the importance of alternative pathways such as aldehyde oxidases (AOX) or N-methyltransferases (NMT) in bioactivation
Nihal Kuş et al.
The journal of physical chemistry. A, 119(24), 6296-6308 (2015-05-31)
The structure, infrared spectrum, and photochemistry of 5-hydroxyquinoline (5HQ) were studied by matrix isolation infrared spectroscopy, complemented by theoretical calculations performed at the DFT(B3LYP)/6-311++G(d,p) level of approximation. According to the calculations, the trans conformer of 5HQ (with the OH group
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