139521
2-(2-氯乙基)-1-甲基吡咯烷 盐酸盐
99%
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关于此项目
经验公式（希尔记法）:
C7H14ClN · HCl
化学文摘社编号:
分子量:
184.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
260-395-2
Beilstein/REAXYS Number:
6148386
MDL number:
产品名称
2-(2-氯乙基)-1-甲基吡咯烷 盐酸盐, 99%
InChI key
KCQMALZNENFGKK-UHFFFAOYSA-N
InChI
1S/C7H14ClN.ClH/c1-9-6-2-3-7(9)4-5-8;/h7H,2-6H2,1H3;1H
SMILES string
Cl[H].CN1CCCC1CCCl
assay
99%
mp
98-102 °C (lit.)
functional group
chloro
Quality Level
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Application
2-(2-Chloroethyl)-1-methylpyrrolidine hydrochloride was used in the synthesis of N-[2-(1-methylpyrrolidin-2-yl)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl) amide. It was used as reagent during the synthesis of 1-methyl-2-[2-[2-(2-phenylethyl)phenoxy]ethyl]pyrrolidine hydrochlochloride.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
N Tanaka et al.
Chemical & pharmaceutical bulletin, 48(2), 245-255 (2000-03-08)
A series of [2-(omega-phenylalkyl)phenoxy]alkylamines was synthesized and their receptor binding affinity was examined in vitro. These compounds showed an affinity for serotonin-2 (5-HT2) and dopamine-2 (D2) receptors. [2-(2-phenylethyl)phenoxy]alkylamine derivatives with a pyrrolidine or piperidine moiety in the structure showed higher
Shejin Zhu et al.
Bioorganic & medicinal chemistry, 14(9), 3131-3143 (2006-01-18)
6-Substituted 8,9-dimethoxy-2,3-methylenedioxy-6H-dibenzo[c,h][2,6]naphthyridin-5-ones were synthesized and evaluated for topoisomerase I-targeting activity and cytotoxicity. Several of these reversed lactam analogues of ARC-111 exhibited exceptional cytotoxicity with IC50 values ranging from 0.5 to 3.0 nM. In contrast to topotecan, no resistance was observed
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