139564
1,2,7,8-二环氧辛烷
97%
别名:
1,7-Octadiene bisoxide, 1,7-Octadiene diepoxide, 2,2′-(1,4-Butanediyl)bis[oxirane]
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关于此项目
经验公式（希尔记法）:
C8H14O2
化学文摘社编号:
分子量:
142.20
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
219-375-9
MDL number:
产品名称
1,2,7,8-二环氧辛烷, 97%
InChI key
LFKLPJRVSHJZPL-UHFFFAOYSA-N
InChI
1S/C8H14O2/c1(3-7-5-9-7)2-4-8-6-10-8/h7-8H,1-6H2
SMILES string
C(CCC1CO1)CC2CO2
assay
97%
form
liquid
refractive index
n20/D 1.445 (lit.)
bp
240 °C (lit.)
density
0.997 g/mL at 25 °C (lit.)
Quality Level
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Application
- Removal of GenX by APTES functionalized diepoxyoctane cross-linked chitosan beads: Cross-linked and aminated chitosan beads were synthesized using 1,2:7,8-diepoxyoctane and 3-aminopropyl triethoxysilane. These beads were studied for their efficiency in removing GenX, a problematic environmental pollutant, demonstrating a potential application in water treatment technologies (M Vakili, F Gholami, HM Zwain, W Wang… - Journal of …, 2023 - Elsevier).
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Carc. 1B - Muta. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
208.4 °F - closed cup
flash_point_c
98 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
X Zhao
Journal of biomaterials science. Polymer edition, 17(4), 419-433 (2006-06-14)
Hyaluronic acid (hyaluronan, HA) has many medical applications as a biomaterial. To enhance its biostability, a novel hydrogel of cross-linked hyaluronic acid was prepared using a double cross-linking process, which involves building cross-linkages between hydroxyl group pairs and carboxyl group
E H Vock et al.
Mutation research, 441(1), 85-93 (1999-05-04)
The time-dependent dose-response relationships for the induction of DNA double-strand breaks (DSB) assessed by pulsed-field gel electrophoresis (PFGE) and for viability (evaluated by the MTT cytotoxicity test) were investigated in order to discriminate between genotoxic and cytotoxic mechanisms of DNA
Cristina Pungartnik et al.
Genetics and molecular research : GMR, 1(1), 79-89 (2004-02-14)
The sensitivity responses of seven pso mutants of Saccharomyces cerevisiae towards the mutagens N-nitrosodiethylamine (NDEA), 1,2:7,8-diepoxyoctane (DEO), and 8-hydroxyquinoline (8HQ) further substantiated their allocation into two distinct groups: genes PSO1 (allelic to REV3), PSO2 (SNM1), PSO4 (PRP19), and PSO5 (RAD16)
J T Millard et al.
Biochemistry, 40(35), 10677-10685 (2001-08-29)
Diepoxyalkanes form interstrand cross-links in DNA oligomers preferentially at 5'-GNC sites. We have examined cross-linking by 1,2,3,4-diepoxybutane (DEB) and 1,2,7,8-diepoxyoctane (DEO) within a fragment of the 5S RNA gene of Xenopus borealis in both the free and nucleosomal states. Sites
D J Eide et al.
Molecular and cellular biology, 5(1), 1-6 (1985-01-01)
The mutation e1662 is an allele of the Caenorhabditis elegans unc-54 gene induced with the difunctional alkylating agent 1,2,7,8-diepoxyoctane. unc-54 encodes the major myosin heavy chain isozyme of body wall muscle cells. Filter-transfer hybridization and DNA sequence analysis show that
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