Merck
CN

143219

Sigma-Aldrich

4-溴苯肼 盐酸盐

99%

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别名:
1-(4-Bromophenyl)hydrazine hydrochloride, 2-(4-Bromophenyl)hydrazinium chloride, 4-Bromophenylhydrazine monohydrochloride, p-Bromophenylhydrazine monohydrochloride
线性分子式:
BrC6H4NHNH2·HCl
CAS号:
分子量:
223.50
Beilstein:
3565838
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

99%

形式

powder

mp

220-230 °C (dec.) (lit.)

SMILES string

Cl.NNc1ccc(Br)cc1

InChI

1S/C6H7BrN2.ClH/c7-5-1-3-6(9-8)4-2-5;/h1-4,9H,8H2;1H

InChI key

RGGOWBBBHWTTRE-UHFFFAOYSA-N

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应用

4-Bromophenylhydrazine hydrochloride was used as reagent in the synthesis of:
  • acylsulfonamides and acylsulfamides
  • 9-bromo-2-ethenyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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T1503
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Michael P Winters et al.
Bioorganic & medicinal chemistry letters, 18(6), 1926-1930 (2008-03-01)
A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. One potent orally bioavailable inhibitor had excellent PK properties and was active in a lung injury
Xu Xie et al.
European journal of medicinal chemistry, 40(7), 655-661 (2005-06-07)
The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for human tumor cell lines. The syntheses were accomplished applying Stille coupling for the introduction
Siva Doddi et al.
Journal of fluorescence, 26(6), 1939-1949 (2016-11-01)
We report the synthesis and characterization of a new fluorescent dyad SP-DPP-SP(9) via efficient palladium-catalyzed Sonogashira coupling of prop-2-yn-1-yl 3-(3',3'dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)propanoatespiropyran, SP(8), a well known photochromic accepter, with 3,6-bis(5-bromothiophen-2-yl)-2,5-bis((R)-2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione, DPP(4), a highly fluorescent donor. Under visible light exposure the SP unit
Ilkoo Noh et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(3), 1700481-1700481 (2018-03-30)
A noninvasive and selective therapy, photodynamic therapy (PDT) is widely researched in clinical fields; however, the lower efficiency of PDT can induce unexpected side effects. Mitochondria are extensively researched as target sites to maximize PDT effects because they play crucial

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