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Merck
CN

15404

N-Boc-1,4-丁二胺

≥97.0% (GC/NT)

别名:

N-(4-氨丁基)氨基甲酸叔丁酯, N-Boc-1,4-二氨基丁烷

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关于此项目

线性分子式:
(CH3)3COCONH(CH2)4NH2
化学文摘社编号:
68076-36-8
分子量:
188.27
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
57647412
MDL number:
MFCD00210019
Beilstein/REAXYS Number:
1937878

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产品名称

N-Boc-1,4-丁二胺, ≥97.0% (GC/NT)

InChI

1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)

SMILES string

NCCCCNC(OC(C)(C)C)=O

InChI key

ZFQWJXFJJZUVPI-UHFFFAOYSA-N

assay

≥97.0% (GC/NT)

reaction suitability

reagent type: cross-linking reagent

refractive index

n20/D 1.460

density

0.984 g/mL at 20 °C (lit.)

functional group

Boc
amine

Quality Level

100

相关类别

Application

  • 羧基-硅烷涂覆氧化铁纳米颗粒：详述采用N-Boc-1,4-丁二胺修饰氧化铁纳米颗粒用于成像和药物递送(D Stanicki, S Boutry, S Laurent, et al., 2014)。访问文章。

Other Notes

药理活性化合物的制备。亚精胺类似物的制备。C4-间隔基的引入。

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

228.2 °F - closed cup

flash_point_c

109.0 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
015906/2
047234/1
045093/1
043011/1
015356/1

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Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential
L I Kruse et al.
Journal of medicinal chemistry, 32(2), 409-417 (1989-02-01)
In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for tubulin binding affinity, in vitro cytotoxicity against cultured mouse B-16 cells, and ability to prolong lifespan
Anand Divakaran et al.
Journal of medicinal chemistry, 61(20), 9316-9334 (2018-09-27)
As regulators of transcription, epigenetic proteins that interpret post-translational modifications to N-terminal histone tails are essential for maintaining cellular homeostasis. When dysregulated, "reader" proteins become drivers of disease. In the case of bromodomains, which recognize N-ε-acetylated lysine, selective inhibition of
Shaohui Deng et al.
Science advances, 6(29), eabb4005-eabb4005 (2020-08-25)
Controlled release of CRISPR-Cas9 ribonucleoprotein (RNP) and codelivery with other drugs remain a challenge. We demonstrate controlled release of CRISPR-Cas9 RNP and codelivery with antitumor photosensitizer chlorin e6 (Ce6) using near-infrared (NIR)- and reducing agent-responsive nanoparticles in a mouse tumor
Regina Holm et al.
Macromolecular rapid communications, 36(23), 2083-2091 (2015-09-08)
In this work, the synthesis of polypeptoid-block-polypeptide copolymers (block copolypept(o)ides) based on bifunctional initiators is described, which introduces a distinct chemical entity at the connection between both blocks. With a view towards redox-sensitive block copolypept(o)ides, a cystamine-based initiator was used
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