158186
乙二胺-N,N′-二乙酸
≥98%
别名:
EDDA, N,N′-乙烯二甘氨酸
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关于此项目
线性分子式:
HOOCCH2NHCH2CH2NHCH2COOH
化学文摘社编号:
分子量:
176.17
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
EC Number:
227-105-6
Beilstein/REAXYS Number:
1778355
MDL number:
产品名称
乙二胺-N,N′-二乙酸, ≥98%
InChI key
IFQUWYZCAGRUJN-UHFFFAOYSA-N
InChI
1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)
SMILES string
OC(=O)CNCCNCC(O)=O
assay
≥98%
mp
224 °C (dec.) (lit.)
functional group
amine
carboxylic acid
Quality Level
Application
乙二胺-N，N′-二乙酸（EDDA）是一种螯合剂，可用于合成：
- 具有高蛋白酶体抑制性能的二元和三元铜（II）配合物。
- 可以与氨基酸、肽或DNA单元络合的Pd（EDDA）配合物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Levente K Meszaros et al.
Dalton transactions (Cambridge, England : 2003), 40(23), 6260-6267 (2011-02-26)
6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous
Hyun-Shik Chang et al.
Environmental science & technology, 40(16), 5089-5094 (2006-09-08)
Permanganate has been used for oxidation of nuclear wastes containing chelating agents such as ethylenediaminetetraacetic and nitrilotriacetic acids (EDTA and NTA) to improve separation of radionuclides and heavy metals from the wastes, butthe mechanisms of degradation of these and related
Clara L Santos-Cuevas et al.
Nuclear medicine communications, 29(8), 741-747 (2008-08-30)
The gastrin-releasing peptide receptor (GRP-R) is expressed in several normal human tissues and is overexpressed in various human tumors including breast, prostate, small-cell lung cancer and pancreatic cancer. Recently, 99mTc-EDDA/HYNIC-[Lys]-bombesin (99mTc-HYNIC-BN) was reported as a radiopharmaceutical with high stability in
Alma D Miranda-Olvera et al.
Bioconjugate chemistry, 18(5), 1560-1567 (2007-08-02)
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position
Jelena M Vujić et al.
European journal of medicinal chemistry, 45(9), 3601-3606 (2010-06-24)
Four novel bidentate N,N'-ligand precursors, including O,O'-dialkyl esters (alkyl = ethyl, n-propyl, n-butyl and n-pentyl), L1 x 2 HCl-L4 x 2 HCl, of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid dihydrochloride [(S,S)-H(4)eddl]Cl(2) and the corresponding palladium(II) complexes 1-4, were prepared and characterized by IR, (1)H
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