产品名称
1,2,4-苯三酚, ReagentPlus®, 99%
InChI key
GGNQRNBDZQJCCN-UHFFFAOYSA-N
InChI
1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H
SMILES string
Oc1ccc(O)c(O)c1
product line
ReagentPlus®
assay
99%
form
solid
mp
140 °C (subl.) (lit.)
Quality Level
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General description
1,2,4-苯三酚也称为羟基氢醌。它是存在于烘焙咖啡豆中的苯的中间代谢物。它具有诱变作用,并会通过生成活性氧而导致DNA单链断裂。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Generation of hydrogen peroxide from hydroxyhydroquinone and its inhibition by superoxide dismutase
Hiramoto K, et al.
Journal of Oleo Science, 50(1), 21-28 (2001)
DNA breakage induced by 1, 2, 4-benzenetriol: relative contributions of oxygen-derived active species and transition metal ions
Li AS, et al.
Free Radical Biology & Medicine, 30(9), 943-956 (2001)
Rolis Chien-Wei Hou et al.
Journal of biomedical science, 13(1), 89-99 (2005-11-26)
Hydroxyhydroquinone or 1,2,4-benzenetriol (BT) detected in the beverages has a structure that coincides with the water-soluble form of a sesame lignan, sesamol. We previously showed that sesame antioxidants had neuroprotective abilities due to their antioxidant properties and/or inducible nitric oxide
Karolina Nordin et al.
Applied and environmental microbiology, 71(11), 6538-6544 (2005-11-05)
Arthrobacter chlorophenolicus A6, a previously described 4-chlorophenol-degrading strain, was found to degrade 4-chlorophenol via hydroxyquinol, which is a novel route for aerobic microbial degradation of this compound. In addition, 10 open reading frames exhibiting sequence similarity to genes encoding enzymes
Tohru Yamaguchi et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 18(6), 408-414 (2007-10-24)
Coffee is rich in chlorogenic acids (CGA), whose metabolites may have beneficial effects such as anti-hypertensive effects. However, trial results concerning the effects of coffee on blood pressure (BP) are not consistent. A recent study suggested that hydroxyhydroquinone (HHQ), produced
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