Quality Level
assay
98%
mp
277-280 °C (lit.)
functional group
carboxylic acid
SMILES string
OC(=O)c1cnc2ccccc2c1
InChI
1S/C10H7NO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6H,(H,12,13)
InChI key
DJXNJVFEFSWHLY-UHFFFAOYSA-N
General description
The antibacterial activity of 3-quinolinecarboxylic acid derivatives were evaluated.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
M P Wentland et al.
Journal of medicinal chemistry, 27(9), 1103-1108 (1984-09-01)
A series of novel 3-quinolinecarboxylic acid derivatives have been prepared and their antibacterial activity evaluated. These derivatives are characterized by fluorine attached to the 6-position and substituted amino groups appended to the 1- and 7-positions. Structure-activity relationship studies indicate that
Antonello Mai et al.
Journal of medicinal chemistry, 49(23), 6897-6907 (2006-12-13)
Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly reduce the S. cerevisiae cell growth, thus miming the effect of GCN5 deletion mutant. Tested on
Ximei Liang et al.
Ecotoxicology (London, England), 24(7-8), 1566-1573 (2015-04-22)
The presence of antibiotics including norfloxacin in the aquatic environment may cause adverse effects in non-target organisms. But the toxic mechanisms of fluoroquinolone to fish species are still not completely elucidated. Thus, it is essential to investigate the response of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 177148-25G | 04061833320358 |
| 177148-1G | 04061826671283 |
| 177148-5G | 04061838753144 |