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文件

178500

3-甲基-1,2-环戊二酮

Name: 3-甲基-1,2-环戊二酮
Brand: ALDRICH

99%

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所有图片(1)

别名:

2-羟基-3-甲基-2-环戊烯酮, 槭树内酯

经验公式（希尔记法）:

C₆H₈O₂

CAS号:

765-70-8

分子量:

112.13

Beilstein:

2076520

EC 号:

212-154-8

MDL编号:

MFCD00001417

PubChem化学物质编号:

24850751

NACRES:

NA.22

检测方案

99%

形式

solid

mp

104-108 °C (lit.)

SMILES string

CC1CCC(=O)C1=O

InChI

1S/C6H8O2/c1-4-2-3-5(7)6(4)8/h4H,2-3H2,1H3

InChI key

OACYKCIZDVVNJL-UHFFFAOYSA-N

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一般描述

3-Methyl-1,2-cyclopentanedione is present in coffee and is capable of scavenging peroxynitrite. It also has anti-inflammatory effects.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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The potential value of natural antioxidative treatment in glaucoma.

M Mozaffarieh et al.

Survey of ophthalmology, 53(5), 479-505 (2008-10-22)

Glaucomatous optic neuropathy implies loss of retinal ganglion cells, including their axons, and a major tissue remodeling, especially in the optic nerve head. Although increased intraocular pressure is a major risk factor for glaucomatous optic neuropathy, there is little doubt

Peroxisome proliferator-activated receptor gamma agonist action of 3-methyl-1,2-cyclopentanedione.

Seo Young Choi et al.

Biochimica et biophysica acta, 1770(12), 1612-1619 (2007-10-13)

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily that plays a pivotal role in regulating inflammatory gene expression. The purpose of this study was to investigate the effects of coffee extract, 3-methyl-1,2-cyclopentanedione (3-MCP) on PPARs in

Selective peroxynitrite scavenging activity of 3-methyl-1,2-cyclopentanedione from coffee extract.

Ae Ra Kim et al.

The Journal of pharmacy and pharmacology, 54(10), 1385-1392 (2002-10-25)

It has been known that reactive oxygen and nitrogen species such as nitric oxide (NO), superoxide radical (*O2-) and their byproduct peroxynitrite (ONOO-) induce cellular and tissue injury, ultimately resulting in several human diseases. In this study, we examined scavenging

3-methyl-1,2-cyclopentanedione down-regulates age-related NF-kappaB signaling cascade.

Jae Heun Chung et al.

Journal of agricultural and food chemistry, 55(16), 6787-6792 (2007-07-17)

Activation of the redox-sensitive transcription factor, nuclear factor-kappa B (NF-kappaB), plays a central role in inflammation and aging processes by inducing pro-inflammatory genes. The present study was designed to unravel the molecular mechanisms underlying the anti-inflammation effects of 3-methyl-1,2-cyclopentanedione (3-MCP)

Enantiomeric deoxycholic acid: total synthesis, characterization, and preliminary toxicity toward colon cancer cell lines.

Bryson W Katona et al.

The Journal of organic chemistry, 72(24), 9298-9307 (2007-10-26)

Deoxycholic acid (DCA) is an endogenous secondary bile acid implicated in numerous pathological conditions including colon cancer formation and progression and cholestatic liver disease. DCA involvement in these disease processes results partly from its ability to modulate signaling cascades within

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