193291
2-氯嘧啶
95%
别名:
2-氯-1,3-嘧啶, 嘧啶-2-酰氯
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关于此项目
经验公式（希尔记法）:
C4H3ClN2
化学文摘社编号:
分子量:
114.53
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-020-2
Beilstein/REAXYS Number:
107171
MDL number:
产品名称
2-氯嘧啶, 95%
InChI key
UNCQVRBWJWWJBF-UHFFFAOYSA-N
InChI
1S/C4H3ClN2/c5-4-6-2-1-3-7-4/h1-3H
SMILES string
Clc1ncccn1
assay
95%
form
crystals
bp
75-76 °C/10 mmHg (lit.)
mp
63-66 °C (lit.)
functional group
chloro
Quality Level
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Application
2-氯嘧啶可用于合成：
- 新 双（2-（嘧啶-2-基）乙氧基）烷烃
- 4′-（1,1′-（5-（2-甲氧基苯氧基）-[2,2′-联嘧啶基]-4,6-二基）双（1H-吡唑-3,1-二基））二苯胺荧光染料，可用作蛋白质测定的生物传感器
- 顺式-和 反式-氢化吡咯并[2,3]吡啶衍生物
- 2-氨基-4-杂芳基嘧啶
General description
2-氯嘧啶可与芳基卤化物发生经钴催化的交叉偶联反应。
Other Notes
残留物为 2-羟基嘧啶
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
208.4 °F - closed cup
flash_point_c
98 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Vangavaragu Jhansi Rani et al.
Archiv der Pharmazie, 345(8), 663-669 (2012-05-18)
The pyrimidine nucleus is an important component of nucleic acids (DNA and RNA) and vitamins (B(2) and folic acid). It is evident from the literature that pyrimidine derivatives possess a wide spectrum of biological activities such as antioxidant, anticancer, antibacterial
Matthew G Bursavich et al.
Organic letters, 7(19), 4113-4116 (2005-09-09)
[reaction: see text] An expedient synthesis of diverse 2-amino-4-heteroarylpyrimidines via a 2-chloropyrimidine intermediate is described. A series of potentially biologically active analogues have been synthesized in two parallel steps to afford focused arrays.
Igor Goljer et al.
Chirality, 21(7), 681-691 (2008-09-17)
Reaction of (S)- or (R)-3-aminoquinuclidine with 2-chloropyrimidine or 2-bromopyrimidine led to an unexpected formation of both cis- and trans-octahydropyrrolo [2,3]pyridine derivatives. A single-step synthesis of two of the four stereoisomers of these octahydropyrrolo[2,3]pyridine derivatives provides a convenient way of generating
Vikas S Padalkar et al.
Chemistry Central journal, 5, 72-72 (2011-11-10)
Fluorescent dyes with biocompatible functional group and good fluorescence behavior are used as biosensor for monitoring different biological processes as well as detection of protein assay. All reported fluorophore used as sensors are having high selectivity and sensitivity but till
Carina Sollert et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(14), 5380-5386 (2015-02-18)
The Ru-catalysed C2-H arylation of indoles and pyrroles by using boronic acids under oxidative conditions is reported. This reaction can be applied to tryptophan derivatives and tolerates a wide range of functional groups on both coupling partners, including bromides and
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