产品名称
4-氯-N-甲基苯胺, 97%
InChI key
XCEYKKJMLOFDSS-UHFFFAOYSA-N
InChI
1S/C7H8ClN/c1-9-7-4-2-6(8)3-5-7/h2-5,9H,1H3
SMILES string
CNc1ccc(Cl)cc1
assay
97%
form
liquid
refractive index
n20/D 1.584 (lit.)
bp
239 °C (lit.)
density
1.169 g/mL at 25 °C (lit.)
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
125.6 °F - closed cup
flash_point_c
52 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
C Varshneya et al.
Toxicology letters, 31(2), 107-111 (1986-05-01)
White leghorn cockerels were fed a diet containing 0, 400, 800 and 1600 ppm of malathion for 90 days. Malathion O,O-dimethyl S-(1,2-dicarbethoxy) ethyl phosphorodithioate) at 800 and 1600 ppm caused a significant decrease in body weights. There was a significant
M Weiner et al.
Drug metabolism and disposition: the biological fate of chemicals, 8(3), 139-142 (1980-05-01)
Hepatic metabolism of aniline, p-chloro-N-methylaniline, and aminopyrine was determined in control male, New Zealand White rabbits or those bearing VX2 carcinoma (a prostaglandin-secreting tumor). In addition, the levels of cyclic AMP and cyclic GMP in the liver and the concentration
S Cottrell et al.
Xenobiotica; the fate of foreign compounds in biological systems, 20(7), 711-726 (1990-07-01)
1. Because of the low concentration of cytochrome P-450 in avocado fruit, microsomal fractions were prepared using polyethylene glycol aggregation and low-speed centrifugation, thus avoiding the need for high-speed centrifugation of large volumes of post-mitochondrial supernatant. Recoveries of cytochrome P-450
Brian W Budzik et al.
Bioorganic & medicinal chemistry letters, 20(4), 1363-1367 (2010-01-26)
A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were readily accessible via solution-phase synthesis which resulted in the rapid identification of key structure-activity relationships
One-pot synthesis of N-methylindoles from N-methylanilines and of benzofurans from phenols using transition-metal carbene X-H insertion reactions.
Honey MA, et al.
Tetrahedron, 65(44), 8995-9001 (2009)
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