Merck
CN

220108

Sigma-Aldrich

异香草酸

97%

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别名:
3-羟基-4-甲氧基苯甲酸
线性分子式:
HOC6H3(OCH3)CO2H
CAS号:
分子量:
168.15
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

97%

形式

solid

mp

250-253 °C (lit.)

SMILES string

COc1ccc(cc1O)C(O)=O

InChI

1S/C8H8O4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3,(H,10,11)

InChI key

LBKFGYZQBSGRHY-UHFFFAOYSA-N

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一般描述

Rate of oxidation of isovanillic acid by washed cells of Pseudomonas putida has been reported.

应用

Isovanillic acid has been used in the synthesis of opiate alkaloid precursor, dihydrothebainone.

法规信息

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M R Jeffers et al.
Microbiology (Reading, England), 143 ( Pt 6), 1975-1981 (1997-06-01)
A methyltransferase enzyme catalysing the 3-O-methylation of isovanillic acid (3-hydroxy-4-methoxybenzoic acid) by S-adenosylmethionine (SAM) was identified in Phanerochaete chrysosporium and purified. Gel filtration indicated an M(r) of 71,000 and SDS-PAGE showed that the enzyme was composed of two subunits of
Widiastuti Setyaningsih et al.
Food chemistry, 288, 221-227 (2019-03-25)
Fifteen phenolic compounds were determined in rice grains by ultrasound assisted extraction and ultra-performance liquid chromatography with photodiode array detection. Primarily, an UAE method has been developed and validated for the extraction of phenolics from rice grains. For the optimization
Preparation of oxygenated phenylacetic acids.
Weller DD, et al.
The Journal of Organic Chemistry, 49(11), 2061-2063 (1984)
Motohiro Nishimura et al.
Journal of bioscience and bioengineering, 102(2), 124-127 (2006-10-10)
Strain NL15-2K was isolated from soil by screening for bacteria capable of catabolizing lignin-related aromatic acids. This isolate was identified as a Streptomyces sp. on the basis of morphology and an analysis of its 16S rRNA gene sequence. NL15-2K utilized
Miguel A Providenti et al.
Journal of bacteriology, 188(11), 3862-3869 (2006-05-19)
In Comamonas testosteroni strain BR6020, metabolism of isovanillate (iVan; 3-hydroxy-4-methoxybenzoate), vanillate (Van; 4-hydroxy-3-methoxybenzoate), and veratrate (Ver; 3,4-dimethoxybenzoate) proceeds via protocatechuate (Pca; 3,4-dihydroxybenzoate). A 13.4-kb locus coding for the catabolic enzymes that channel the three substrates to Pca was cloned. O

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