Merck
CN

227714

Sigma-Aldrich

3,4,5-三甲氧基甲苯

97%

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别名:
5-甲基邻苯三酚三甲醚
线性分子式:
(CH3O)3C6H2CH3
CAS号:
分子量:
182.22
Beilstein:
1953791
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

97%

折射率

n20/D 1.523 (lit.)

bp

117-118 °C/5 mmHg (lit.)

mp

24-26 °C (lit.)

密度

1.082 g/mL at 25 °C (lit.)

SMILES string

COc1cc(C)cc(OC)c1OC

InChI

1S/C10H14O3/c1-7-5-8(11-2)10(13-4)9(6-7)12-3/h5-6H,1-4H3

InChI key

KCIZTNZGSBSSRM-UHFFFAOYSA-N

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应用

3,4,5-Trimethoxytoluene was used as a substructure model compound in the reaction of trimethoprim with free available chlorine (i.e. HOCl).

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

165.2 °F - closed cup

闪点(°C)

74 °C - closed cup

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Ah-Reum Han et al.
Chemistry & biodiversity, 5(2), 346-351 (2008-02-23)
Bioassay-guided fractionation of the root extract of Asarum sieboldii led to the isolation of the four active compounds (-)-sesamin (1), (2E,4E,8Z,10E)-N-(2-methylpropyl)dodeca-2,4,8,10-tetraenamide (2), kakuol (3), and '3,4,5-trimethoxytoluene' (=1,2,3-trimethoxy-5-methylbenzene; 4), in terms of inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production. Compounds
Chia-Lin Lee et al.
PloS one, 7(5), e37897-e37897 (2012-06-06)
In a structure-activity relationship (SAR) study, 3-methoxy-1,4-phenanthrenequinones, calanquinone A (6a), denbinobin (6b), 5-OAc-calanquinone A (7a) and 5-OAc-denbinobin (7b), have significantly promising cytotoxicity against various human cancer cell lines (IC(50) 0.08-1.66 µg/mL). Moreover, we also established a superior pharmacophore model for
Michael C Dodd et al.
Water research, 41(3), 647-655 (2006-12-19)
Trimethoprim (TMP), one of the antibacterials most frequently detected in municipal wastewaters and surface waters, reacts readily with free available chlorine (i.e., HOCl) at pH values between 3 and 9 (e.g., the pH-dependent apparent second-order rate constant, k''(app)=5.6 x 10(1)M(-1)s(-1)
Olga V Zalomaeva et al.
Dalton transactions (Cambridge, England : 2003), 46(16), 5202-5209 (2017-04-01)
The selective oxidation of methoxy/methyl-substituted arenes to the corresponding benzoquinones has been first realized using aqueous hydrogen peroxide as a green oxidant, acid tetrabutylammonium salts of the γ-Keggin divanadium-substituted phosphotungstate [γ-PW
Dandan Pu et al.
Foods (Basel, Switzerland), 9(4) (2020-04-08)
The key aroma compounds in smoke-cured pork leg were characterized by gas chromatography-olfactometry coupled with aroma extract dilution analysis (GC-O/AEDA), odor activity value (OAV), recombination modeling, and omission tests. Ranking analysis showed that pork leg smoke-cured for 18 days had

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