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Merck
CN

248975

α-甲氧基苯乙酸

99%

别名:

DL-α-甲氧基苯乙酸, O-甲基-DL-扁桃酸, MOPA

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关于此项目

线性分子式:
C6H5CH(OCH3)COOH
化学文摘社编号:
分子量:
166.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
230-300-9
Beilstein/REAXYS Number:
2209197
MDL number:
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产品名称

α-甲氧基苯乙酸, 99%

InChI key

DIWVBIXQCNRCFE-UHFFFAOYSA-N

InChI

1S/C9H10O3/c1-12-8(9(10)11)7-5-3-2-4-6-7/h2-6,8H,1H3,(H,10,11)

SMILES string

COC(C(O)=O)c1ccccc1

assay

99%

form

solid

bp

165 °C/18 mmHg (lit.)

mp

69-71 °C (lit.)

functional group

carboxylic acid
ether
phenyl

Quality Level

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Application

α-甲氧基苯乙酸用于HPLC法对两种非对映体酯进行对映体拆分

General description

通过HPLC在手性固定相上将α-甲氧基苯乙酸的对映体拆分为酰胺衍生物。α-甲氧基苯乙酸也称Trost手性酸

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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2-Methoxy-2-(1-naphthyl) propionic acid, a powerful chiral auxiliary for enantioresolution of alcohols and determination of their absolute configurations by the< sup> 1</sup> H NMR anisotropy method.
Harada N, et al.
Tetrahedron Asymmetry, 11(6), 1249-1253 (2000)
Resolution of a-arylacetic acid enantiomers on two chiral stationary phases.
McDaniel DM and Snider BG.
Journal of Chromatography A, 404, 123-132 (1987)
Bin Chang et al.
Journal of clinical microbiology, 53(10), 3318-3324 (2015-08-14)
Streptococcus pneumoniae colonizes the nasopharyngeal mucus in healthy people and causes otitis media, pneumonia, bacteremia, and meningitis. In this study, we analyzed an S. pneumoniae strain that caused 7 repeated pneumonia episodes in an 80-month-old patient with cerebral palsy during
Radoslaw Laufer et al.
Bioorganic & medicinal chemistry, 22(17), 4968-4997 (2014-07-22)
TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido moieties at
Weidong Liu et al.
Chembiochem : a European journal of chemical biology, 16(6), 924-929 (2015-03-11)
A meso-diaminopimelate dehydrogenase (DAPDH) from Clostridium tetani E88 (CtDAPDH) was found to have low activity toward the D-amino acids other than its native substrate. Site-directed mutagenesis similar to that carried out on the residues mutated by Vedha-Peters et al. resulted

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