258881
2-氨基-1,3,4-噻二唑
97%
别名:
1,3,4-噻二唑-2-胺
方案
97%
表单
powder
mp
188-191 °C (dec.) (lit.)
溶解性
water: soluble 25 mg/mL, clear, colorless
SMILES字符串
Nc1nncs1
InChI
1S/C2H3N3S/c3-2-5-4-1-6-2/h1H,(H2,3,5)
InChI key
QUKGLNCXGVWCJX-UHFFFAOYSA-N
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一般描述
2-氨基-1,3,4-噻二唑（供体）与 2,3-二氯-5,6-二氰--p -苯醌、-p -氯醌、-o -氯醌、-p -溴苯腈和氯苯胺酸（受体）形成电荷转移络合物 。2-氨基-1,3,4-噻二唑 [氨基噻二唑 (NSC 4728)] 对体内 L1210 腹水细胞 的嘌呤和嘧啶核苷酸池的影响 已有报道 。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
L M Scheidel et al.
Virology, 158(1), 1-7 (1987-05-01)
Previous work from this laboratory has demonstrated a correlation between the inhibition by ribavirin (Rbv), mycophenolic acid (MPA), or 2-amino thiadiazole (TDA) of Sindbis virus replication in Aedes albopictus mosquito cells and a reduction in cellular GTP levels. This reduction
Eszter Szennyes et al.
Carbohydrate research, 472, 33-41 (2018-11-20)
Annulated C-β-d-glucopyranosyl heterocycles were synthesized and tested as inhibitors of glycogen phosphorylase. 2-(β-d-Glucopyranosyl)-1H-imidazo[4,5-b]pyridine was formed by ring-closure of O-perbenzoylated C-β-d-glucopyranosyl formic acid with 2,3-diaminopyridine in the presence of triphenylphosphite. Cyclisations of bromomethyl 2,3,4,6-tetra-O-benzoyl-β-d-glucopyranosyl ketone with a set of 2-aminoheterocycles resulted
P J Elson et al.
Investigational new drugs, 6(2), 97-103 (1988-06-01)
One hundred and forty-four evaluable patients with recurrent or metastatic renal cell carcinoma (RCC) were treated with vinblastine infusion (n = 35), L-alanosine (n = 36), acivicin (n = 27), or aminothiadiazole (n = 46). Observed objective response rates of
M Gaber et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 62(1-3), 526-531 (2005-11-01)
Charge transfer (CT) complexes formed between 2-amino-1,3,4-thiadiazole as donor and 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), p-chloranil (p-CHL), o-chloranil (o-CHL), p-bromanil (BRL) and chloranilic acid (CHA) as acceptors, have been studied spectrophotometrically. Benesi-Hildebrand and Job continuous variation methods were applied to the determination of
G Mazzone et al.
Farmaco (Societa chimica italiana : 1989), 48(9), 1207-1224 (1993-09-01)
We prepared some series of 2-(alkylaminoacyl) derivatives of 2-amino-1,3,4-thiadiazoles. Most terms were subjected to a biological screening showing a local anesthetic activity both in infiltration and trunkular tests. For some of the assayed derivatives, the activity was comparable to that
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