方案
≥97%
表单
crystals
折射率
n20/D 1.5775 (lit.)
沸点
139-140 °C/14 mmHg (lit.)
mp
26-29 °C (lit.)
官能团
sulfoxide
储存温度
2-8°C
SMILES字符串
CS(=O)c1ccccc1
InChI
1S/C7H8OS/c1-9(8)7-5-3-2-4-6-7/h2-6H,1H3
InChI key
JXTGICXCHWMCPM-UHFFFAOYSA-N
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一般描述
(R)- 甲基苯基亚砜是一种重要的药物中间体。
应用
甲基苯基亚砜可用于合成：
- 同位素标记的1,3-二噻烷，一种有用的标记合成子
- 奈非那韦，强效HIV蛋白酶抑制剂
- 亚砜亚胺和溶剂-水分配的研究中
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
186.8 °F - closed cup
闪点(°C)
86 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M H Abraham et al.
Journal of pharmaceutical sciences, 83(8), 1085-1100 (1994-08-01)
A general linear solvation energy equation has been used to analyze published partition coefficients in the systems water-octanol (613 solutes), water-hexadecane (370 solutes), water-alkane (200 solutes), and water-cyclohexane (170 solutes). The descriptors used in the equation are R2, an excess
Sadagopan Raghavan et al.
The Journal of organic chemistry, 75(2), 498-501 (2009-12-17)
An asymmetric synthesis of nelfinavir is described starting from acrolein and (S)-methyl phenyl sulfoxide. The key features include (a) stereoselective preparation of a beta-protected amino-gamma,delta-unsaturated sulfoxide by the reaction of an alpha-sulfinyl carbanion with an unsaturated t-butyl sulfinylimine, (b) stereoselective
Aldrichimica Acta, 18, 3-3 (1985)
Nathalie Sauvonnet et al.
The Journal of cell biology, 168(1), 155-163 (2004-12-30)
Endocytosis is critical for many cellular functions. We show that endocytosis of the common gammac cytokine receptor is clathrin independent by using a dominant-negative mutant of Eps15 or RNA interference to knock down clathrin heavy chain. This pathway is synaptojanin
T Egawa et al.
The Journal of biological chemistry, 275(45), 34858-34866 (2000-08-18)
Reaction of ferric native myoglobin (Mb) with hydrogen peroxide (H(2)O(2)) was studied by the aid of stopped-flow rapid-scan spectrophotometry. In contrast to the results in previous studies where compound I was reported to be undetectable, both sperm whale and horse
Chromatograms
application for HPLC
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