26569
2-氯代三苯甲基氯
≥97.0% (AT)
别名:
氯(2-氯苯基)二苯甲烷
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关于此项目
经验公式（希尔记法）:
C19H14Cl2
化学文摘社编号:
分子量:
313.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
255-647-3
Beilstein/REAXYS Number:
1983914
MDL number:
产品名称
2-氯代三苯甲基氯, ≥97.0% (AT)
InChI key
JFLSOKIMYBSASW-UHFFFAOYSA-N
InChI
1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
SMILES string
Clc1ccccc1C(Cl)(c2ccccc2)c3ccccc3
assay
≥97.0% (AT)
form
solid
mp
130-135 °C
functional group
chloro
phenyl
Quality Level
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Application
2-氯三苯甲酰氯用于获得保护肽片段，可应用于头-尾环肽的制备或肽片段的缩合 。
Other Notes
保护基团试剂，用于形成温和裂解的酯的羧酸。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Shinichiro F Ichise et al.
Acta biomaterialia, 94, 361-371 (2019-06-15)
Collagen is the most abundant protein in the animal kingdom and has a unique triple-helical structure. It not only provides mechanical strength to tissues, but also performs specific biological functions as a multifaceted signaling molecule. Animal-derived collagen is therefore widely
K Barlos et al.
International journal of peptide and protein research, 37(6), 513-520 (1991-06-01)
The esterification of 2-chlorotrityl chloride resin with Fmoc-amino acids in the presence of DIEA is studied under various conditions. High esterification yields are obtained using 0.6 equiv. Fmoc-amino acid/mmol resin in DCM or DCE, in 25 min, at room temperature.
Jie Luo et al.
Journal of the American Society for Mass Spectrometry, 30(9), 1643-1653 (2019-06-07)
Chemical cross-linking combined with mass spectrometry (CL-MS) is a powerful method for characterizing the architecture of protein assemblies and for mapping protein-protein interactions. Despite its proven utility, confident identification of cross-linked peptides remains a formidable challenge, especially when the peptides
Asker Y Khapchaev et al.
Journal of peptide science : an official publication of the European Peptide Society, 22(11-12), 673-681 (2016-10-05)
Myosin light chain kinase (MLCK) is a key regulator of various forms of cell motility including smooth muscle contraction, cell migration, cytokinesis, receptor capping, secretion, etc. Inhibition of MLCK activity in endothelial and epithelial monolayers using cell-permeant peptide Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys (PIK
Sogol Kangarlou et al.
Pharmaceutical biology, 55(1), 277-285 (2016-12-13)
Curcumin, a naturally occurring polyphenol, has been extensively studied for its broad-spectrum anticancer effects. The potential benefits are, however, limited due to its poor water solubility and rapid degradation which result in low bioavailability on administration. This study encapsulates curcumin
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