275247
4-（2-氨乙基）苯磺酰胺
99%
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关于此项目
线性分子式:
H2NCH2CH2C6H4SO2NH2
化学文摘社编号:
分子量:
200.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
252-501-0
MDL number:
产品名称
4-（2-氨乙基）苯磺酰胺, 99%
InChI key
FXNSVEQMUYPYJS-UHFFFAOYSA-N
InChI
1S/C8H12N2O2S/c9-6-5-7-1-3-8(4-2-7)13(10,11)12/h1-4H,5-6,9H2,(H2,10,11,12)
SMILES string
NCCc1ccc(cc1)S(N)(=O)=O
assay
99%
form
powder
mp
150-152 °C (lit.)
functional group
amine
Quality Level
Gene Information
human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)
mouse ... Car13(71934), Car5a(12352)
Application
4-(2-氨基乙基)苯磺酰胺用于开发一个模型系统，以研究微流体芯片的实现，用于生物化学相互作用的傅里叶变换测量。
General description
用抑制剂4-(2-氨基乙基)苯磺酰胺治疗人肝细胞癌(HCC)细胞。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
P Megyeri et al.
Immunology, 86(4), 629-635 (1995-12-01)
Monocytes freshly isolated from human blood produced large amounts of superoxide when triggered by phorbol ester. After monocytes were cultured for 18-24 hr in endotoxin-free, non-adherent conditions, they produced low amounts of superoxide. Addition of lipopolysaccharide (LPS), interferon-gamma (IFN-gamma), tumour
Su-jong Yu et al.
Acta pharmacologica Sinica, 32(7), 912-920 (2011-06-15)
The hypoxic condition within large or infiltrative hypovascular tumors produces intracellular acidification, which could activate many signaling pathways and augment cancer cell growth and invasion. Carbonic anhydrase-IX (CA-IX) is an enzyme lowering pH. This study is to examine whether hypoxia
Layne D Williams et al.
Analytical chemistry, 82(14), 6025-6031 (2010-06-24)
Surface plasmon resonance (SPR) is a popular technique for label-free detection of biomolecular interactions at a surface. SPR yields quantitative kinetic association and dissociation constants of surface interactions such as the binding of two molecular species, one present in the
C H Mastrangelo et al.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2010, 5318-5321 (2010-11-26)
New developments in microfluidic chip technology enable the construction of chemical spectrum analyzers that can probe the binding interactions between chemical entities. In this paper we report the implementation of a microfluidic chip suitable for Fourier transform measurements of biochemical
Gayan S Jayawickrama et al.
PloS one, 13(4), e0196404-e0196404 (2018-04-25)
The mammalian kynurenine aminotransferase (KAT) enzymes are a family of related isoforms that are pyridoxal 5'-phosphate-dependent, responsible for the irreversible transamination of kynurenine to kynurenic acid. Kynurenic acid is implicated in human diseases such as schizophrenia where it is found
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