279277
N-羟甲基烟酰胺
98%
别名:
3-吡啶羧酸 N-羟甲酰胺
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关于此项目
经验公式（希尔记法）:
C7H8N2O2
化学文摘社编号:
分子量:
152.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-668-4
MDL number:
Assay:
98%
InChI key
JRFKIOFLCXKVOT-UHFFFAOYSA-N
InChI
1S/C7H8N2O2/c10-5-9-7(11)6-2-1-3-8-4-6/h1-4,10H,5H2,(H,9,11)
SMILES string
OCNC(=O)c1cccnc1
assay
98%
mp
152-154 °C (lit.)
functional group
amide, hydroxyl
General description
A quantitative determination of N-(hydroxymethyl)nicotinamide in tablets and basic solutions along with nicotinic acid by thin-layer chromatography-densitometric method has been reported. N-(Hydroxymethyl)nicotinamide is an antimicrobial agent.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Urszula Hubicka et al.
Journal of AOAC International, 91(5), 1186-1190 (2008-11-05)
A thin-layer chromatography (TLC)-densitometric method was developed to determine N-(hydroxymethyl)nicotinamide in tablets and basic solutions along with nicotinic acid. Analysis was performed on silica gel F254 plates using chloroform-ethanol (2 + 3, v/v) mobile phase. The densitometric observations were made
H K Zhang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 27(8), 629-631 (1992-01-01)
N-Hydroxymethyl-nicotinamide, an antimicrobic agent was prepared in good yield by treating nicotinamide with excess of formaldehyde in the presence of potassium carbonate. The condensation reaction was studied under different conditions, changing the amount of formaldehyde, with different kinds of bases
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