296783
1H-苯并咪唑-5-羧酸
96%
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关于此项目
经验公式（希尔记法）:
C8H6N2O2
化学文摘社编号:
分子量:
162.15
UNSPSC Code:
12352100
eCl@ss:
32151902
PubChem Substance ID:
NACRES:
NA.22
MDL number:
产品名称
1H-苯并咪唑-5-羧酸, 96%
SMILES string
OC(=O)c1ccc2[nH]cnc2c1
InChI
1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)
InChI key
COYPLDIXZODDDL-UHFFFAOYSA-N
assay
96%
mp
>300 °C (lit.)
functional group
carboxylic acid
Quality Level
Application
5-Benzimidazolecarboxylic acid has been used in the preparation of:
- 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester
- piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone
General description
Drug-specific monoclonal antibodies were produced against the very small drug hapten, 5-benzimidazolecarboxylic acid.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Ajit Jadhav et al.
Probe Reports from the NIH Molecular Libraries Program, 2010 Mar 4 (Updated 2011 Mar 11) (2011-07-08)
15-hydroxyprostaglandin dehydrogenase (15-PGDH; HPGD) is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation. The anabolic pathways of prostaglandins are well-characterized, especially with respect to regulation of the cyclooxygenase (COX) enzymes. In
E S Medlock et al.
The Anatomical record, 207(1), 31-41 (1983-09-01)
Mouse fetal liver was studied ultrastructurally to identify and characterize the developing hepatic parenchyma or prehepatocyte which may be responsible for producing the liver hemopoietic environment. It was observed that as the liver develops, there is close association of endodermal
E Moran et al.
Journal of immunological methods, 271(1-2), 65-75 (2002-11-26)
Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans
Xiaofei Chen et al.
Biomaterials science, 3(6), 870-878 (2015-07-30)
Herein, hyperbranched poly(ethylene glycol)-based supramolecular nanoparticles with pH-sensitive properties were designed and used for targeted drug delivery. Via host-guest recognition between benzimidazole anchored poly(ethylene glycol)-hyperbranched polyglycerol (PEG-HPG-BM) and folic acid modified CD (FA-CD), targeted supramolecular nanoparticles (TSNs) were fabricated. At
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