质量水平
方案
97%
表单
liquid
折射率
n20/D 1.498 (lit.)
沸点
203 °C/752 mmHg (lit.)
mp
23-25 °C (lit.)
密度
1.192 g/mL at 25 °C (lit.)
SMILES字符串
c1c[nH]nn1
InChI
1S/C2H3N3/c1-2-4-5-3-1/h1-2H,(H,3,4,5)
InChI key
QWENRTYMTSOGBR-UHFFFAOYSA-N
一般描述
2 H -1,2,3-三唑是 1 H -1,2,3-三唑的互变异构体。1H-1,2,3-三唑通过分子间质子转移机制有效地促进了质子在聚合物电解质膜中的传导。
应用
- 结晶框架材料：对三唑羧酸配体的研究已经证明其在智能晶体框架材料中的应用，特别是在荧光传感和对硝基苯酚的催化还原方面，说明其在化学传感和环境应用中具有实用性（Lv et al., 2023）。
- PXR受体调节：1H-1,2,3-三唑-4-羧酰胺已被优化为PXR受体的强效选择性逆激动剂和拮抗剂，对受体特异性药物的设计具有参考价值（Li et al., 2022）。
- 大规模合成：利用改良的Sakai反应大规模合成Notum抑制剂说明H-1,2,3-三唑在生化试剂生产中很重要，对于医学研究和药物开发是必不可少的（Atkinson et al., 2022）。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
224.6 °F - closed cup
闪点(°C)
107 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Kashif Mahmood et al.
International journal of molecular sciences, 20(24) (2019-12-11)
NAC (NAM (no apical meristem), ATAF1/2, and CUC2 (cup-shaped cotyledon)) proteins are one of the largest families of plant-specific transcription factors, and this family is present in a wide range of land plants. Here, we have investigated the role of
Paco Pino et al.
PLoS pathogens, 3(8), e115-e115 (2007-09-06)
Toxoplasma gondii is an aerobic protozoan parasite that possesses mitochondrial antioxidant enzymes to safely dispose of oxygen radicals generated by cellular respiration and metabolism. As with most Apicomplexans, it also harbors a chloroplast-like organelle, the apicoplast, which hosts various biosynthetic
Bertrand Boson et al.
PLoS pathogens, 7(7), e1002144-e1002144 (2011-08-05)
Hepatitis C virus (HCV) assembly remains a poorly understood process. Lipid droplets (LDs) are thought to act as platforms for the assembly of viral components. The JFH1 HCV strain replicates and assembles in association with LD-associated membranes, around which viral
Atul Bhardwaj et al.
Nature communications, 8(1), 1-1 (2017-02-25)
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases. The amino-acid sequence and structural similarity between inducible cyclooxygenase-2 and housekeeping cyclooxygenase-1 isoforms present a significant challenge to
Zhen Zhou et al.
Journal of the American Chemical Society, 127(31), 10824-10825 (2005-08-04)
We report 1H-1,2,3-triazole as an active group to dramatically enhance proton conduction in a polymer electrolyte membrane (PEM). The conductivities of a poly(4-vinyl-1H-1,2,3-triazole) membrane without any acidic dopants are about 105 times greater than those of poly(4-vinylimidazole) in dry air
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