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359793

Z-Lys-OH

Name: Z-Lys-OH
Brand: ALDRICH

98%

别名:

N_α-(苄氧羰基)-L-赖氨酸, N_α-Cbz-L-赖氨酸, N_α-Z-L-赖氨酸

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关于此项目

线性分子式:

NH₂(CH₂)₄CH(NHCOOCH₂C₆H₅)COOH

化学文摘社编号:

2212-75-1

分子量:

280.32

EC Number:

218-662-6

UNSPSC Code:

12352200

PubChem Substance ID:

24862109

Beilstein/REAXYS Number:

2153826

MDL number:

MFCD00038204

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属性

assay

98%

optical activity

[α]20/D −13±2°, c = 2 in 0.2 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

mp

226-231 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NCCCC[C@H](NC(=O)OCc1ccccc1)C(O)=O

InChI

1S/C14H20N2O4/c15-9-5-4-8-12(13(17)18)16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m0/s1

InChI key

OJTJKAUNOLVMDX-LBPRGKRZSA-N

说明

Application

用于简便制备 L-α-氨基己二酸的离析物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Cationic Poly(Amino Acid) Vaccine Adjuvant for Promoting Both Cell-Mediated and Humoral Immunity Against Influenza Virus.

Jong-Woo Lim et al.

Advanced healthcare materials, 8(2), e1800953-e1800953 (2018-12-15)

Powerful adjuvants to augment vaccine efficacy with a less immunogenic vaccine system are in great demand. In this study, a novel squalene-based cationic poly(amino acid) adjuvant (CASq) that elicits both cellular (Th1) and humoral (Th2) immune responses is developed. CASq

An expanded genetic code facilitates antibody chemical conjugation involving the lambda light chain.

Akifumi Kato et al.

Biochemical and biophysical research communications, 546, 35-39 (2021-02-10)

Most of the currently approved therapeutic antibodies are of the immunoglobulin gamma (IgG) κ isotype, leaving a vast opportunity for the use of IgGλ in medical treatments. The incorporation of designer amino acids into antibodies enables efficient and precise manufacturing

Characterization of Nalpha-benzyloxycarbonyl-L-lysine oxidizing enzyme from Rhodococcus sp. AIU Z-35-1.

Kimiyasu Isobe et al.

Journal of bioscience and bioengineering, 104(3), 218-223 (2007-10-30)

An oxidase catalyzing conversion of N(alpha)-benzyloxycarbonyl-L-lysine (N(alpha)-Z-L-lysine) to N(alpha)-benzyloxycarbonyl-L-aminoadipate-delta-semialdehyde (N(alpha)-Z-L-AASA) was purified from Rhodococcus sp. AIU Z-35-1, and its properties were revealed. This enzyme catalyzed an oxidative deamination of the epsilon-amino group of N(alpha)-acyl-L-lysine and the alpha-amino group of N(epsilon)-acyl-L-lysine.

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全球贸易项目编号

货号	GTIN
359793-5G	04061832641980