363529
苄基 (R)-(-)-缩水甘油基醚
99%
别名:
(R)-苄氧甲基环氧乙烷
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关于此项目
经验公式（希尔记法）:
C10H12O2
化学文摘社编号:
分子量:
164.20
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3588399
Assay:
99%
Form:
liquid
InChI
1S/C10H12O2/c1-2-4-9(5-3-1)6-11-7-10-8-12-10/h1-5,10H,6-8H2/t10-/m0/s1
SMILES string
C(OCc1ccccc1)[C@H]2CO2
InChI key
QNYBOILAKBSWFG-JTQLQIEISA-N
assay
99%
form
liquid
optical activity
[α]20/D −5.4°, c = 5 in toluene
refractive index
n20/D 1.517 (lit.)
density
1.077 g/mL at 25 °C (lit.)
functional group
ether, phenyl
storage temp.
2-8°C
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Application
用于制备康帕丁和洛伐他汀的内酯片段。制备顺-1,3-多元醇、二脱氧核苷和螺缩醛氰醇的手性子。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
The Journal of Organic Chemistry, 53, 4495-4495 (1988)
Journal of the Chemical Society. Chemical Communications, 291-291 (1993)
Synthesis, 539-539 (1989)
E Abushanab et al.
Journal of medicinal chemistry, 32(1), 76-79 (1989-01-01)
1',2'-seco-2',3'-Dideoxycytidine (12), -guanosine (14), -adenosine (16), and -inosine (18) were prepared from (R)-benzylglycidol as potential anti-HIV agents. When compared to ddAdo in protecting ATH8 cells, they were found to be inactive.
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