Merck
CN
所有图片(3)

文件

379506

Sigma-Aldrich

三(2,3-环氧丙基)异氰尿酸酯

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所有图片(3)
别名:
1,3,5-三（环氧-2-基甲基）-1,3,5-三嗪-2,4,6-三酮, 异氰尿酸三缩水甘油酯, 甲状腺球蛋白
经验公式（希尔记法）:
C12H15N3O6
CAS号:
2451-62-9
分子量:
297.26
EC 号:
219-514-3
MDL编号:
MFCD00080670
PubChem化学物质编号:
24863665
NACRES:
NA.23

形式

powder

质量水平

200

SMILES string

O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4

InChI

1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2

InChI key

OUPZKGBUJRBPGC-UHFFFAOYSA-N

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相关类别

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 1B - Skin Sens. 1 - STOT RE 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Jing-Ping Wang et al.
Toxicology and applied pharmacology, 273(1), 110-120 (2013-08-21)
In this work, we demonstrated that the growth of human non-small-cell-lung-cancer cells H460 and A549 cells can be inhibited by low concentrations of an epoxide derivative, teroxirone, in both in vitro and in vivo models. The cytotoxicity was mediated by
G Atassi et al.
Cancer treatment reviews, 11 Suppl A, 99-110 (1984-03-01)
As a follow-up to our initial results on the antineoplastic activity of alpha-1,3,5-triglycidyl-s-triazinetrione (alpha TGT, NSC-296934, Teroxirone), many new epoxyde derivatives were tested against murine tumours, mostly against P388 leukaemia, to determine their antineoplastic role and to characterize their specific
J A Neidhart et al.
Cancer treatment reports, 68(9), 1115-1119 (1984-09-01)
Teroxirone is a novel triepoxide, synthesized as an alkylator and showing a broad spectrum of preclinical activity. It has good cytotoxic activity against sublines of P388 and L1210 leukemias resistant to another alkylating agent, cyclophosphamide. Thirty-six patients received teroxirone as
Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint factory.
C S Munro et al.
Contact dermatitis, 26(1), 59-59 (1992-01-01)
P Dombernowsky et al.
Cancer chemotherapy and pharmacology, 11(1), 59-61 (1983-01-01)
alpha-1,3,5-Triglycidyl-s-triazinetrione (TGT) is a triepoxide derivative with alkylating properties discovered by random screening. TGT has been found to be active against a wide variety of murine tumors, including a P388 subline resistant to cyclophosphamide. The starting dose in this phase-I
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