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经验公式(希尔记法):
C9H16N2O
化学文摘社编号:
分子量:
168.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
243-331-8
MDL number:
产品名称
2,2,5,5-四甲基-3-吡咯啉-3-甲酰胺, 99%
InChI key
ACFYUJLIWIDSFM-UHFFFAOYSA-N
InChI
1S/C9H16N2O/c1-8(2)5-6(7(10)12)9(3,4)11-8/h5,11H,1-4H3,(H2,10,12)
SMILES string
CC1(C)NC(C)(C)C(=C1)C(N)=O
assay
99%
mp
180-182 °C (lit.)
functional group
amide
Quality Level
Application
2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide may be used in the synthesis of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide and 3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy free radical.
General description
2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide is a carboxamide of a hydrogenated pyrrole derivative. It is a sterically hindered amino compound having amino alkyl side chain. The antiarrhythmic activity of some of the derivatives of 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide have been evaluated.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ampika Phutim-Mangkhalthon et al.
Photodiagnosis and photodynamic therapy, 31, 101747-101747 (2020-03-23)
Photodynamic therapy improves oral mucositis treatment. The reactive oxygen species (ROS) generated from this reaction could contribute to an anti-inflammatory effect by suppressing inflammatory cells. To evaluate the anti-inflammatory effect of photodynamic therapy using guaiazulene and a red laser in
Rei Miyano et al.
Journal of bioscience and bioengineering, 129(4), 508-513 (2019-12-16)
A new nitrogen-containing compound, trichothioneic acid, was discovered from the metabolites of fungal strain FKI-7573 using a mass spectrometry screening method guided by odd number of molecular weights, which indicates compounds that contain an odd number of nitrogen atoms. Strain
Nitroxide free radicals in the hydrogenated pyrrole series.
Rozantsev EG, et al.
Russian Chemical Bulletin, 15(4), 638-641 (1966)
O H Hankovszky et al.
Journal of medicinal chemistry, 29(7), 1138-1152 (1986-07-01)
N-(omega-Aminoalkyl)-2,2,5,5-tetramethyl-3-pyrroline- or -pyrrolidine-3-carboxamides were acylated on the primary amino group of the side chain by means of reactive acid derivatives (acid chlorides, activated esters, phthalic anhydrides, phthalimide, 2-alkyl-4H-3,1-benzoxazin-4-ones) or they were alkylated by forming the Schiff bases and subsequent sodium
Keisuke Nakamura et al.
Journal of clinical biochemistry and nutrition, 49(2), 87-95 (2011-10-08)
The aim of the present study is to compare different analytical methods for singlet oxygen and to discuss an appropriate way to evaluate the yield of singlet oxygen photogenerated from photosensitizers. Singlet oxygen photogenerated from rose bengal was evaluated by
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