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文件

411035

6-羟基黄酮

Name: 6-羟基黄酮
Brand: ALDRICH

98%

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经验公式（希尔记法）:

C₁₅H₁₀O₃

CAS号:

6665-83-4

分子量:

238.24

EC 号:

229-704-8

MDL编号:

MFCD00017329

PubChem化学物质编号:

24865723

NACRES:

NA.22

检测方案

98%

形式

solid

mp

234-236 °C (lit.)

SMILES string

Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3

InChI

1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H

InChI key

GPZYYYGYCRFPBU-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208) , Gabra2(29706)

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Structure of 6-hydroxyflavone.

Seetharaman J and Rajan SS.

Acta Crystallographica Section C, Structural Chemistry, 48(9), 1714-1715 (1992)

6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells.

Xing Wang et al.

PloS one, 10(3), e0116409-e0116409 (2015-03-20)

Inflammatory responses by kidney mesangial cells play a critical role in the glomerulonephritis. The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypetin, apigenin and myricetin were investigated on rat mesangial cells with lipopolysaccharide

The flavonoid 6-hydroxyflavone prevention of cisplatin-induced nephrotoxicity.

Zia Ud Din et al.

Histology and histopathology, 35(10), 1197-1209 (2020-09-11)

In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model of nephrotoxicity. Male Sprague-Dawley rats weighing 200-250 g were included in the study. 6-Hydroxyflavone was daily administered at 25 and 50 mg/kg

An insight into the binding of 6-hydroxyflavone with hen egg white lysozyme: a combined approach of multi-spectroscopic and computational studies.

Sourav Das et al.

Journal of biomolecular structure & dynamics, 37(15), 4019-4034 (2018-10-14)

The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and computational methods. Steady state fluorescence studies indicated that static quenching mechanism is involved in the binding of 6HF with HEWL, which was further

Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone.

Angélica Flores-Flores et al.

Drug development research, 80(2), 218-229 (2018-11-06)

Previously, we described tracheal rat rings relaxation by several flavonoids, being 6-hydroxyflavone (6-HOF) the most active derivative of the series. Thus, its mechanism of action was determined in an ex vivo tracheal rat ring bioassay. The anti-asthmatic effect was assayed

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