Name: (1<I>S</I>,4<I>S</I>)-(-)-2-Boc-2,5-二氮杂双环[2.2.1]庚烷
Brand: ALDRICH

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About This Item

经验公式（希尔记法）:

C₁₀H₁₈N₂O₂

CAS Number:

113451-59-5

分子量:

198.26

MDL编号:

MFCD01569250

UNSPSC代码:

12352005

PubChem化学物质编号:

24870862

NACRES:

NA.22

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方案

95%

旋光性

[α]22/D −44°, c = 1 in chloroform

mp

74-76 °C (lit.)

SMILES字符串

CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2

InChI

1S/C10H18N2O2/c1-10(2,3)14-9(13)12-6-7-4-8(12)5-11-7/h7-8,11H,4-6H2,1-3H3/t7-,8-/m0/s1

InChI key

UXAWXZDXVOYLII-YUMQZZPRSA-N

应用

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane may be used in the preparation of 2-boc-5-(4-nitrophenyl)-2,5-diaza-bicyclo[2.2.1]heptane by reacting with p-nitrobenzene.
It may also be used to develop:

indazolylpyrazolo[1,5-a]pyrimidine analogs based B-Raf inhibitors
CCR2 antagonists
α4β2 nicotinic acetylcholine receptor (nAChR) partial agonists
azabicyclic sulfonamide based 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors