(S)-(-)-4-羟基-2-吡咯烷酮

Name: (<I>S</I>)-(-)-4-羟基-2-吡咯烷酮
Brand: ALDRICH

97%

别名:

(S)-β-羟基-γ-丁内酰胺

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₄H₇NO₂

CAS Number:

68108-18-9

分子量:

101.10

Beilstein:

1524192

MDL编号:

MFCD00273370

UNSPSC代码:

12352005

PubChem化学物质编号:

24871604

NACRES:

NA.22

质量水平

100

方案

97%

旋光性

[α]23/D −43°, c = 1 in ethanol

mp

156-159 °C (lit.)

官能团

hydroxyl

SMILES字符串

O[C@@H]1CNC(=O)C1

InChI

1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m0/s1

InChI key

IOGISYQVOGVIEU-VKHMYHEASA-N

一般描述

4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine.

应用

(S)-(−)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:

Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.