540242
(R)-(-)-1,2-丙二醇
96%
别名:
(R)-(-)-丙二醇, 甲甘醇
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关于此项目
线性分子式:
CH3CH(OH)CH2OH
化学文摘社编号:
分子量:
76.09
UNSPSC Code:
12352001
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1718872
Assay:
96%
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3/t3-/m1/s1
SMILES string
C[C@@H](O)CO
InChI key
DNIAPMSPPWPWGF-GSVOUGTGSA-N
assay
96%
optical activity
[α]20/D −16.5°, neat
optical purity
ee: 98% (GLC)
refractive index
n20/D 1.434 (lit.)
bp
186-188 °C/765 mmHg (lit.)
density
1.04 g/mL at 25 °C (lit.)
functional group
hydroxyl
Quality Level
Other Notes
(R)-(-)-1,2-丙二醇通过瘤胃微生物菌群而在牛瘤胃液中发生代谢，并释放出含硫气体。
Legal Information
经Sterling Pharma Solutions Limited授权使用Jacobsen HKR技术制造。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
217.4 °F - closed cup
flash_point_c
103 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Yang Zhao et al.
Nature communications, 8, 14180-14180 (2017-01-26)
Many naturally occurring biomolecules, such as amino acids, sugars and nucleotides, are inherently chiral. Enantiomers, a pair of chiral isomers with opposite handedness, often exhibit similar physical and chemical properties due to their identical functional groups and composition, yet show
Ruminal fermentation of propylene glycol and glycerol.
Trabue S, et al.
Journal of Agricultural and Food Chemistry, 55(17), 7043-7051 (2007)
Ying-Zheng Zhao et al.
Cancer letters, 330(1), 74-83 (2012-11-29)
Multidrug resistance (MDR) is one of the major reasons for the failure of cancer chemotherapy. A newly reported liposome carrier, propylene glycol liposomes (EPI-PG-liposomes) were made to load epirubicin (EPI) which enhanced EPI absorption in MDR tumor cells to overcome
Kenneth B Sloan et al.
Journal of cosmetic science, 64(3), 181-192 (2013-06-12)
It would be useful to develop a surrogate for animal skin, which could be use to predict flux through human skin. The fluxes (and physicochemical properties) of sunscreens and other compounds from propylene glycol (PG):water (AQ), 30:70, through human skin
A A Melo et al.
The Journal of laryngology and otology, 127(4), 359-363 (2013-02-15)
To determine whether the administration of mitomycin C prevents propylene glycol exposure from inducing middle-ear cholesteatoma and otitis media, in a rat model. Twenty-four Wistar rats underwent intratympanic injections on days 1, 8 and 15, via the tympanic membrane pars
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